Evidence map›Paper›PMID 39650857›Full record

ArticleMicroelectronic engineering2018

Laser micromachining of tapered optical fibers for spatially selective control of neural activity.

Alessandro Rizzo, Enrico Domenico Lemma, Filippo Pisano, Marco Pisanello, Leonardo Sileo, Massimo De Vittorio, Ferruccio Pisanello

Abstract read
In one paragraph

Article in Microelectronic engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandro RizzoIstituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Enrico Domenico LemmaIstituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Filippo PisanoIstituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Marco PisanelloIstituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Leonardo SileoIstituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Massimo De Vittorio *Istituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.
Ferruccio Pisanello *Istituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti snc, 73010 Arnesano, Italy.

Funding

Novel optrodes for large-scale electrophysiology and site-specific stimulationU01NS094190 · NINDS · HARVARD MEDICAL SCHOOL · PI ASSAD, JOHN, BERDONDINI, LUCA · 2015 to 2017
$1.6M
European Research Council 677683European Research Council 692943NINDS NIH HHS U01 NS094190
6 · The paper itself

Abstract

Tapered and micro-structured optical fibers (TFs) recently emerged as a versatile tool to obtain dynamically addressable light delivery for optogenetic control of neural activity in the mammalian brain. Small apertures along a metal-coated and low-angle taper allow for controlling light delivery sites in the neural tissue by acting on the coupling angle of the light launched into the fiber. However, their realization is typically based on focused ion beam (FIB) milling, a high-resolution but time-consuming technique. In this work we describe a laser micromachining approach to pattern TFs edge in a faster, more versatile and cost-effective fashion. A four-axis piezoelectric stage is implemented to move and rotate the fiber during processing to realize micropatterns all-around the taper, enabling for complex light emission geometries with TFs.

Indexed as

AblationCoupling angleDirect laser writingLaser micromachiningTapered fiber

Identifiers

PMID39650857
PMCPMC7617094

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.