ArticleDigital discovery2023
A fully automated platform for photoinitiated RAFT polymerization.
Article in Digital discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Polymerization-Induced Electrostatic Self-Assembly Enables Noncytotoxic Polyplex Formation for Gene Delivery.ACS materials letters · 2026Article
- Self-driving lab for the data-driven design of single-chain polymer nanoparticles.Cell press blue · 2026Article
- A robotic approach to polymerisation kinetics: a case study on copolymerisation parameter estimation.Chemical science · 2026Article
- Challenges and Opportunities in Machine Learning for Light-Emitting Polymers.Macromolecular rapid communications · 2026Review
- Automated active learning to optimize hydrogel drug release profiles.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- Automation-Assisted Photoinduced Atom Transfer Radical Polymerization.ACS polymers Au · 2026Article
- Polyanion Chemistry Engineers Ternary RNA Nanoparticle Structure/Function from the Inside-Out.ACS nano · 2026Article
- Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- SAXS Assistant: Automated SAXS analysis for structural discovery in biologics and polymeric nanoparticles.Biophysical journal · 2025Article
- RAFT with Light: A User Guide to Using Thiocarbonylthio Compounds in Photopolymerizations.ACS polymers Au · 2025Article
- Cross-disciplinary perspectives on the potential for artificial intelligence across chemistry.Chemical Society reviews · 2025Review
- Precision Stealth Nanofibers via PET-RAFT Polymerisation: Synthesis, Crystallization-driven Self-assembly and Cellular Uptake Studies.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- The Role of Artificial Intelligence and Machine Learning in Polymer Characterization: Emerging Trends and Perspectives.Chromatographia · 2025Article
- Mapping Biomaterial Complexity by Machine Learning.Tissue engineering. Part A · 2024Review
- Data-Driven Design of Novel Polymer Excipients for Pharmaceutical Amorphous Solid Dispersions.Bioconjugate chemistry · 2024Article
- Red-Light-Driven Atom Transfer Radical Polymerization for High-Throughput Polymer Synthesis in Open Air.Journal of the American Chemical Society · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Oxygen tolerant polymerizations including Photoinduced Electron/Energy Transfer-Reversible Addition-Fragmentation Chain-Transfer (PET-RAFT) polymerization allow for high-throughput synthesis of diverse polymer architectures on the benchtop in parallel. Recent developments have further increased throughput using liquid handling robotics to automate reagent handling and dispensing into well plates thus enabling the combinatorial synthesis of large polymer libraries. Although liquid handling robotics can enable automated polymer reagent dispensing in well plates, photoinitiation and reaction monitoring require automation to provide a platform that enables the reliable and robust synthesis of various polymer compositions in high-throughput where polymers with desired molecular weights and low dispersity are obtained. Here, we describe the development of a robotic platform to fully automate PETRAFT polymerizations and provide individual control of reactions performed in well plates. On our platform, reagents are automatically dispensed in well plates, photoinitiated in individual wells with a custom-designed lightbox until the polymerizations are complete, and monitored online in real-time by tracking fluorescence intensities on a fluorescence plate reader, with well plate transfers between instruments occurring
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.