Effects of induced subclinical hypocalcemia in early-lactation Holstein cows without milking during infusion on parathyroid hormone and serotonin concentrations.

W S Frizzarini, J P Campolina, M K Connelly, H P Fricke, L L Hernandez

Abstract read

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Article in JDS communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

W S FrizzariniDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.

J P CampolinaDepartmento de Zootecnia, Escola de Veterinaria, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 30161-970, Brazil.

M K ConnellyDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.

H P FrickeDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.

L L HernandezDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition to lactation demands a substantial amount of calcium (Ca) to support colostrum and milk production. Extensive research has been focused on elucidating the interplay between the traditional Ca-parathyroid hormone-vitamin D axis and mammary-derived factors, such as serotonin (5-HT) and parathyroid-hormone-like hormone (PTHLH), in regulating Ca metabolism during the transition period. Here, we investigate the impact of induced subclinical hypocalcemia (SCH) on 5-HT and parathyroid hormone (PTH) concentrations in early-lactation dairy cows under conditions of 24-h milk stasis. Twelve multiparous Holstein cows in early lactation received either continuous intravenous infusion of saline solution or 5% ethylene glycol tetraacetic acid (EGTA) to maintain blood ionized calcium (iCa) below 1 m

Identifiers

PMID39650027

DOI10.3168/jdsc.2024-0589

PMCPMC11624329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.