Evidence map›Paper›PMID 39650010›Full record

ArticleJDS communications2024

Dairy goat sulfadoxine depletion trial in milk and diagnostic accuracy of the Charm Rapid One Step Assay (ROSA) SULF test.

Miranda Hawley, Joe Smith, Kaitlyn Lawson, Jocelyn Jansen, Rex Crawford, Afolakemi Adeniji, Cathy Bauman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JDS communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miranda HawleyOntario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1.
Joe SmithSMART Pharmacology, Iowa State University, Ames, IA 50011.
Kaitlyn LawsonOntario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1.
Jocelyn JansenOntario Ministry of Agriculture, Food and Rural Affairs, Elora, ON, Canada, N1G 2W1.
Rex CrawfordDufferin Veterinary Services, Amaranth, ON, Canada, L9W 0N4.
Afolakemi AdenijiOntario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1.
Cathy BaumanOntario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Canada, currently no antibiotics are approved for use in lactating dairy goats. Trimethoprim sulfadoxine is indicated for the treatment of bacterial pneumonia, enteric and septicemic colibacillosis and salmonellosis, infectious pododermatitis, and septicemias. The aim of this study was to determine the trimethoprim sulfadoxine withdrawal time and evaluate the test accuracy of the Charm Rapid One Step Assay (ROSA) SULF test (Charm Sciences Inc.) at the individual goat level. The study was conducted on 20 visibly healthy Ontario dairy goats. They received trimethoprim sulfadoxine at a dose of 16 mg/kg i.m. once a day for 5 d as the commercially available preparation trimethoprim sulfadoxine (Borgal, Merck Animal Health). Residue levels were measured using liquid chromatography-tandem mass spectrometry and the Charm ROSA SULF. The withdrawal time was calculated using safe concentration linear regression. The determined milk withdrawal time was 60 h.

Identifiers

PMID39650010
PMCPMC11624390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.