ArticleTherapeutic radiology and oncology2023
A retrospective bilateral breast proton pencil beam scanning and photon volumetric arc therapy planning comparison.
Article in Therapeutic radiology and oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Hypofractionated and conventionally fractionated radiotherapy for synchronous bilateral breast cancer: clinical and dosimetric outcomes.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
Background: Advanced bilateral breast cancers with local and regional nodal involvement are rare and challenging to plan due to conflicting demands of conformality, uniformity and sparing of organs at risk such as heart and lungs. Pencil beam scanning (PBS) protons have been shown to provide improved organ at risk (OAR) sparing, conformality and homogeneity compared to photon techniques including three-dimensional conformal radiotherapy, intensity modulated radiation therapy (IMRT), volumetric arc therapy (VMAT), and tomotherapy. We performed a blinded comparison between VMAT and PBS plans and extend this comparison with a case study of a patient win expander Methods: In this case-controlled study, five bilateral breast patients' clinical proton plan datasets were anonymized and replanned using VMAT. Additionally, for one patient with bilateral expanders, we compared two PBS planning techniques that are used clinically. Results: For the similar target volume coverage, significant differences were found for heart and lung sparing, particularly for lower isodoses. For instance, mean lung V5 was 96.7% Conclusions: PBS provides better sparing of heart and lungs compared to VMAT in whole breast, chest wall and expander patients. Further study with more patients is required to validate these conclusions.
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