Evidence map›Paper›PMID 39649616›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment.

Meysam Ahangaran, Nauman Dawalatabad, Cody Karjadi, James Glass, Rhoda Au, Vijaya B Kolachalama

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Meysam AhangaranDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, 72 E. Concord St, Boston, MA, USA - 02118.
Nauman DawalatabadComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, USA - 02139.
Cody KarjadiDepartment of Anatomy and Neurobiology, Boston University Chobanian and Avedisian School of Medicine, 72 E. Concord St, Boston, MA, USA - 02118.
James GlassComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, USA - 02139.
Rhoda AuDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, 72 E. Concord St, Boston, MA, USA - 02118.
Vijaya B KolachalamaDepartment of Medicine, Boston University Chobanian and Avedisian School of Medicine, 72 E. Concord St, Boston, MA, USA - 02118.ORCID 0000-0002-5312-8644

Funding

Utilizing Technology and AI Approaches to Facilitate Independence andResilience in Older AdultsP30AG073104 · NIA · JOHNS HOPKINS UNIVERSITY · PI Alexis Battle · 2021 to 2026
$31.2M
Digital Cognitive Assessment of Preclinical Alzheimer's Disease and Related DementiasR01AG083735 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Rhoda Au, Vijaya B. Kolachalama · 2024 to 2026
$2.4M
Mechanisms of drug-coated balloon therapyR01HL159620 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOLACHALAMA, VIJAYA B. · 2021 to 2024
$2.1M
Cognitive heterogeneity in those with high Alzheimer's Disease RiskR01AG062109 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Rhoda Au, Vijaya B. Kolachalama · 2025 to 2026
$1.6M
NHLBI NIH HHS R01 HL159620NIA NIH HHS P30 AG073104NIA NIH HHS R01 AG062109NIA NIH HHS R01 AG083735
6 · The paper itself

Abstract

Introduction: Digital voice analysis is gaining traction as a tool to differentiate cognitively normal from impaired individuals. However, voice data poses privacy risks due to the potential identification of speakers by automated systems. Methods: We developed a framework that uses weighted linear interpolation of privacy and utility metrics to balance speaker obfuscation and cognitive integrity in cognitive assessments. This framework applies pitch-shifting for speaker obfuscation while preserving cognitive speech features. We tested it on digital voice recordings from the Framingham Heart Study (N=128) and Dementia Bank Delaware corpus (N=85), both containing responses to neuropsychological tests. Results: The tool effectively obfuscated speaker identity while maintaining cognitive feature integrity, achieving an accuracy of 0.6465 in classifying individuals with normal cognition, mild cognitive impairment, and dementia in the FHS cohort. Discussion: Our approach enables the development of digital markers for dementia assessment while protecting sensitive personal information, offering a scalable solution for privacy-preserving voice-based diagnostics.

Identifiers

PMID39649616
PMCPMC11623733

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.