Evidence map›Paper›PMID 39649554›Full record

ArticleImmunometabolism2020

Myeloid Cell Diversity and Impact of Metabolic Cues during Atherosclerosis.

Alexandre Gallerand, Marion I Stunault, Johanna Merlin, Rodolphe R Guinamard, Laurent Yvan-Charvet, Stoyan Ivanov

Abstract read
In one paragraph

Article in Immunometabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandre Gallerand *Mediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.
Marion I Stunault *Mediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.
Johanna Merlin *Mediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.
Rodolphe R GuinamardMediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.
Laurent Yvan-CharvetMediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.
Stoyan IvanovMediterranean center of molecular medicine (C3M)-Université Côte d'Azur-INSERM U1065, Team 13, Nice, 06200, France.

Funding

European Research Council 724838
6 · The paper itself

Abstract

Myeloid cells are key contributors to tissue, immune and metabolic homeostasis and their alteration fuels inflammation and associated disorders such as atherosclerosis. Conversely, in a classical chicken-and-egg situation, systemic and local metabolism, together with receptor-mediated activation, regulate intracellular metabolism and reprogram myeloid cell functions. Those regulatory loops are notable during the development of atherosclerotic lesions. Therefore, understanding the intricate metabolic mechanisms regulating myeloid cell biology could lead to innovative approaches to prevent and treat cardiovascular diseases. In this review, we will attempt to summarize the different metabolic factors regulating myeloid cell homeostasis and contribution to atherosclerosis, the most frequent cardiovascular disease.

Indexed as

atherosclerosisdendritic cellmacrophagemetabolismmonocyte

Identifiers

PMID39649554
PMCPMC7617020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.