Evidence map›Paper›PMID 39649500›Full record

ArticleClinical case reports2024

Cerebral Fat Embolism After Traumatic Long-Bone Fracture: A Case Report.

Mariachiara Ippolito, Vincenzo Benenati, Valentina Gambino, Maria Lapi, Dario Nicosia, Alessandro Pace, Gabriele Presti, Fiammetta Ronga, Noemi Spina, Marco Tutone and 4 more

Abstract read
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mariachiara IppolitoDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.ORCID https://orcid.org/0000-0001-9851-6301
Vincenzo BenenatiDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Valentina GambinoDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Maria LapiDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Dario NicosiaDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Alessandro PaceDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Gabriele PrestiDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Fiammetta RongaDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Noemi SpinaDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Marco TutoneDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Rosaria VanellaDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Antonino FedericoDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Antonino GiarratanoDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.
Andrea CortegianiDepartment of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone Palermo Italy.ORCID https://orcid.org/0000-0003-1416-9993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We here describe a rare case of a 26-year-old male patient, presenting to our hospital after a motorcycle-car accident for the surgical management of long-bone fractures to the tibia and femur and shoulder dislocation and undergoing orthopedic surgery, who postoperatively developed seizure, coma, and respiratory failure due to a cerebral fat embolism. After some hours after the surgery, a loss of consciousness was described by caregivers, and the ICU team was alerted, and the patient was admitted to ICU. Intracranial hemorrhage and stroke were subsequently excluded and, finally, a whole-body computed tomography angiography scan and head magnetic resonance imaging showed lesions consistent with cerebral fat embolism. Patent foramen ovale was then suspected by contrasted echocardiography. An early diagnosis helped to choose the correct management, with early tracheostomy, and to correctly interpret and manage hemodynamic dysregulations. Overall, the care provided lead to positive long-term outcomes, as the patient was discharged alive and successfully completed neurological rehabilitation, regaining many functional abilities. The initial management, diagnostic pathway, and ICU management are here described.

Indexed as

case reportfat embolism syndromeintensive care unittrauma

Identifiers

PMID39649500
PMCPMC11620978

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.