Evidence map›Paper›PMID 39649449›Full record

ReviewInterface focus2024

Optimizing brain protection after cardiac arrest: advanced strategies and best practices.

Ida Giorgia Iavarone, Katia Donadello, Giammaria Cammarota, Fausto D'Agostino, Tommaso Pellis, Erik Roman-Pognuz, Claudio Sandroni, Federico Semeraro, Mypinder Sekhon, Patricia R M Rocco and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Interface focus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. The pulsing brain: part I.Interface focus · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ida Giorgia IavaroneDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Katia DonadelloDepartment of Surgery, Anaesthesia and Intensive Care Unit B, Dentistry, Paediatrics and Gynaecology, University of Verona, University Hospital Integrated Trust of Verona, Verona, Italy.
Giammaria CammarotaAnesthesia and Intensive Care Unit, Azienda Ospedaliero, Universitaria SS Antonio E Biagio E Cesare Arrigo Di Alessandria, Alessandria, Italy.
Fausto D'AgostinoDepartment of Anaesthesia, Intensive Care and Pain Management, Campus Bio MedicoUniversity and Teaching Hospital, Rome, Italy.
Tommaso PellisDepartment of Anaesthesia, Intensive Care and Pain Management, Campus Bio Medico University and Teaching Hospital, Rome, Italy.
Erik Roman-PognuzDepartment of Medical Science, Intensive Care Unit, University Hospital of Cattinara - ASUGI, Trieste Department of Anesthesia, University of Trieste, Trieste, Italy.
Claudio SandroniDepartment of Intensive Care, Emergency Medicine and Anaesthesiology - Fondazione Policlinico Universitario A. Gemelli, IRCCS, Italy; Catholic University of the Sacred Heart, Rome, Italy.
Federico SemeraroDepartment of Anesthesia, Intensive Care and Prehospital Emergency, Maggiore Hospital Carlo Alberto Pizzardi, Bologna, Italy.
Mypinder SekhonDepartment of Medicine, Division of Critical Care Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Patricia R M RoccoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Chiara RobbaDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.ORCID https://orcid.org/0000-0003-1628-3845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrest (CA) is associated with high incidence and mortality rates. Among patients who survive the acute phase, brain injury stands out as a primary cause of death or disability. Effective intensive care management, including targeted temperature management, seizure treatment and maintenance of normal physiological parameters, plays a crucial role in improving survival and neurological outcomes. Current guidelines advocate for neuroprotective strategies to mitigate secondary brain injury following CA, although certain treatments remain subjects of debate. Clinical examination and neuroimaging studies, both invasive and non-invasive neuromonitoring methods and serum biomarkers are valuable tools for predicting outcomes in comatose resuscitated patients. Neuromonitoring, in particular, provides vital insights for identifying complications, personalizing treatment approaches and forecasting prognosis in patients with brain injury post-CA. In this review, we offer an overview of advanced strategies and best practices aimed at optimizing brain protection after CA.

Indexed as

braincardiac arresthypoxic-ischemic brain injuryneuro-prognostication

Identifiers

PMID39649449
PMCPMC11620827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.