Evidence map›Paper›PMID 39649314›Full record

ArticleIndian journal of nephrology

C3 Glomerulonephritis Associated with Monoclonal Gammopathy.

Ana D Piedade, Patricia A Domingues, António S Inácio, Beatriz B Mendes, Lúcia F Parreira

Abstract readCase Reports
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana D PiedadeDepartment of Nephrology, Setubal Hospital Center, Setúbal, Portugal.
Patricia A DominguesDepartment of Nephrology, Setubal Hospital Center, Setúbal, Portugal.
António S InácioDepartment of Nephrology, Setubal Hospital Center, Setúbal, Portugal.
Beatriz B MendesDepartment of Nephrology, Setubal Hospital Center, Setúbal, Portugal.
Lúcia F ParreiraDepartment of Nephrology, Setubal Hospital Center, Setúbal, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C3 glomerulonephritis (C3GN) is rare. It is a proliferative glomerulonephritis resulting from glomerular deposition of complement factors due to dysregulation of the alternative pathway of complement. The association between monoclonal protein production and development of C3GN was described. We report a 74-year-old man with rapid worsening of kidney function and dialysis needed due to C3GN. In this case, serum protein electrophoresis showed no monoclonal spike but serum immunoelectrophoresis showed a lambda light chain monoclonal gammopathy. Once the diagnosis was made, the patient was treated with immunosuppression with complete kidney recovery. This case shows the importance of accurate and prompt diagnosis and appropriate treatment.

Indexed as

C3 glomerulonephritisGlomerulonephritisMembranoproliferative glomerulonephritisMonoclonal gammopathyMonoclonal gammopathy of renal significance

Identifiers

PMID39649314
PMCPMC11618983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.