Evidence map›Paper›PMID 39649312›Full record

ArticleIndian journal of nephrology

NELL-1 Associated Membranous Nephropathy - A Case Series from India.

Yogita Sharma, Akash Jain, Pallav Gupta, Vaibhav Tiwari, Anurag Gupta, Vinant Bhargava, Manish Malik, Ashwani Gupta, Anil Kumar Bhalla, Devinder Singh Rana

Abstract readCase Reports
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yogita SharmaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Akash JainDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Pallav GuptaDepartment of Pathology, Sir Ganga Ram Hospital, New Delhi, India.
Vaibhav TiwariDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Anurag GuptaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Vinant BhargavaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Manish MalikDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Ashwani GuptaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Anil Kumar BhallaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.
Devinder Singh RanaDepartment of Nephrology, Sir Ganga Ram Hospital, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural epidermal growth factor-like 1 (NELL-1) is responsible for a substantial proportion of cases of PLA2R-negative primary membranous nephropathy (MN). To investigate the occurrence, association, and treatment responses, we carried out this ambispective study. In the study, nine (10%) of all patients with MN at our center were found to be NELL-1 positive. On follow up, all patients recieved immunosuppression (steroids, cyclophosphamide or rituximab). Five patients were in complete remission, while one patient had partial remission, two patients had a progressive decline in kidney function, and one patient was lost to follow-up early. No link was found with malignancies, traditional Indian medicines or infection.

Indexed as

glomerulonephritisMembranous nephropathyMNNELL-1nephrotic syndrome

Identifiers

PMID39649312
PMCPMC11618949

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