Evidence map›Paper›PMID 39649246›Full record

ArticleMaterials today. Bio2024

Harnessing hydrogen sulfide in injectable hydrogels that guide the immune response and osteoclastogenesis balance for osteoporosis treatment.

Lianghua Jiang, Yubin Wu, Zonghan Xu, Mingzhuang Hou, Shayang Chen, Chao Cheng, Dan Hu, Daming Lu, Xuesong Zhu, Chong Li

Abstract read
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lianghua JiangDepartment of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, Jiangsu, 215300, China.
Yubin WuDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Zonghan XuDepartment of Orthopedics, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University, Suzhou, 215008, China.
Mingzhuang HouDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Shayang ChenDepartment of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, Jiangsu, 215300, China.
Chao ChengDepartment of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, Jiangsu, 215300, China.
Dan HuDepartment of Orthopedics, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University, Suzhou, 215008, China.
Daming LuDepartment of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, Jiangsu, 215300, China.
Xuesong ZhuDepartment of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Chong LiDepartment of Orthopedics, Affiliated Kunshan Hospital of Jiangsu University, Jiangsu, 215300, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated levels of oxidative stress, inflammation, and a dysregulated osteoclastogenesis balance frequently characterize the microenvironment of osteoporosis, which impedes the processes of healing and repair. Existing treatment approaches are limited in scope and rely primarily on factors and drugs. An injectable hydrogel designed for the ROS-responsive release of H

Indexed as

Bone regenerationH2S-Releasing hydrogelInflammatoryOsteoporosisROS-Responsive

Identifiers

PMID39649246
PMCPMC11625156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.