Evidence map›Paper›PMID 39649223›Full record

Observational studyFrontiers in endocrinology2024

A single-center's uric acid profile in girls with Turner syndrome.

Song Guo, Qiuli Chen, Jun Zhang, Meihua Wei, Rujiang Zheng, Bing Wang, Yanhong Li, Huamei Ma, Xiaoyun Jiang

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Song Guo *Department of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Qiuli Chen *Department of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Jun Zhang *Department of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Meihua WeiDepartment of Child Healthcare, Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China.
Rujiang ZhengDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Bing WangDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Yanhong LiDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Huamei MaDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Xiaoyun JiangDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metabolic disorders are common in individuals with Turner syndrome (TS). Hyperuricemia is associated with metabolic syndrome. This study investigated the serum uric acid (SUA) profile in patients with TS. Methods: A retrospective observational study was conducted with 145 patients with TS. A total of 72 normal girls were in the control group from 2015 to 2024: 86 TS patients were treated with growth hormone (GH), 80 with stanozolol, and 52 with estrogen. Results: Hyperuricemia was present in 33.1% (47/145) of patients with untreated TS and in 16.67% (12/72) of the controls ( Conclusion: Girls with TS showed a slow rising tendency in SUA and SUASDS with age and had higher SUA and SUASDS levels and incidence of hyperuricemia compared to their healthy female peers. The independent risk factors for hyperuricemia in pediatric patients with TS were BMISDS, HOMA-IR, glucose, and eGFR. The incidence of hyperuricemia increased in the first year of stanozolol treatment.

Indexed as

HyperuricemiaTurner SyndromeUric AcidAdolescentCase-Control StudiesChildChild, PreschoolEstrogensFemaleHumansRetrospective StudiesStanozololEstrogensStanozololUric Acidinsulin resistancelipidsserum uric acidstanozololTurner syndrome

Identifiers

PMID39649223
PMCPMC11620862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.