Evidence map›Paper›PMID 39649037›Full record

ArticleCurrent opinion in physiology2020

V1-bypassing thalamo-cortical visual circuits in blindsight and developmental dyslexia.

Samy Rima, Michael Christoph Schmid

Abstract read
In one paragraph

Article in Current opinion in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Functional blindsight and its diagnosis.Frontiers in neurology · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samy RimaUniversité de Fribourg, Switzerland.
Michael Christoph SchmidUniversité de Fribourg, Switzerland.

Funding

European Research Council 637638
6 · The paper itself

Abstract

Vision rests on computations that primarily rely on the parvocellular and magnocellular geniculate relay of retinal signals to V1. Secondary pathways involving superior colliculus, koniocellular lateral geniculate nucleus and pulvinar and their V1-bypassing projections to higher order cortex are known to exist. While they may form an evolutionary old visual system, their contribution to perception and visually guided behaviour remain largely obscure. Recent developments in tract tracing and circuit manipulation technologies provide new insights. Here we discuss how secondary visual pathways mediate residual vision (blindsight) after V1 injury by relaying signals directly into higher order cortical areas. We contrast these findings on blindsight with new studies on dyslexia suggesting that dysfunction of secondary visual pathways might contribute to dyslexic's perceptual difficulties. Emerging from these considerations, secondary visual pathways involving koniocellular LGN may be critical for detection of visual change, whereas pulvinar function appears more linked to visuomotor planning.

Identifiers

PMID39649037
PMCPMC7617028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.