Evidence map›Paper›PMID 39648657›Full record

ReviewImmunotherapy2024

Customizing subcutaneous immunoglobulin administration in primary antibody deficiency: patient-centric care perspectives.

Roger H Kobayashi, Joanna Maltese, Jiří Litzman, Huub Kreuwel, Theresa Zekoll, Ai Lan Kobayashi, Sudhir Gupta

Abstract readReview
In one paragraph

Review in Immunotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roger H KobayashiDivision of Pediatric Immunology and Allergy, School of Medicine, University of California, Los Angeles, CA, USA.
Joanna MalteseMedical Affairs, Octapharma USA, Inc, Paramus, NJ, USA.
Jiří LitzmanDepartment of Clinical Immunology and Allergology, St. Anne's University in Brno, Faculty of Medicine, Masaryk University, Brno, Czechia.
Huub KreuwelMedical Affairs, Octapharma USA, Inc, Paramus, NJ, USA.
Theresa ZekollMedical Affairs, Octapharma AG, Vienna, Austria.
Ai Lan KobayashiMedical Affairs, Midland Pediatrics, Papillion, NE, USA.
Sudhir GuptaDivision of Basic and Clinical Immunology, University of California, Irvine, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report delves into the challenges and potential solutions associated with flexible, customized subcutaneous immunoglobulin (SCIG) infusion regimens for patients with primary antibody deficiency disease (PAD). Advances in the treatment of inborn errors of immunity, particularly PAD, have converted fatal diseases into chronic, complex, long-term conditions that make adherence to treatment a critical issue. Conventional SCIG infusion regimens, while clinically effective, may not always align with the varied lifestyles, changing lifestyles and commitments of patients which can lead to missed doses, diminishing adherence thus posing potential health risks and compromising the overall effectiveness of treatment. For these reasons, it's important to develop flexible infusion regimens tailored to meet individual patient needs. Patient-centric strategies that promote shared decision-making and awareness of patient status not only promote medical efficacy but also enhance the overall patient experience. The authors of this report call attention for a need to shift toward more adaptable and individualized SCIG treatment plans for PAD patients whose needs may change over the long-term course of treatment.

Indexed as

Immunization, PassivePrimary Immunodeficiency DiseasesHumansInfusions, SubcutaneousInjections, SubcutaneousPatient-Centered CarePrecision MedicineCutaquigImmunoglobulin replacement therapypatient-centricprimary antibody deficiency diseaseshared decision-makingsubcutaneous immunoglobulin

Identifiers

PMID39648657
PMCPMC11760218

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.