Trial reportMedicine and science in sports and exercise2025
Effects of Eccentric Exercise of the Extensors on Eccentric Exercise-Induced Muscle Damage of the Flexors in Limbs.
Trial report in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Effects of carbon dioxide hydrate cryotherapy on knee flexor muscle function recovery trajectory after muscle damage: a randomized controlled trial.Frontiers in physiology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe tested the hypothesis that muscle damage protection effect would be induced by its antagonist muscle eccentric exercise.
methodsSedentary young (20-28 yr) men were randomly assigned into six groups; three groups each for arm or leg exercise group ( n = 12/group). One group performed two bouts of 30 maximal eccentric contractions (30MaxEC) of the elbow flexors (EF) or 60 maximal eccentric contractions (60MaxEC) of the knee flexors (KF) using a different arm (contra-EF-EF) or leg (contra-KF-KF) between bouts. The other two groups performed 30MaxEC of the elbow extensors (EE) or 60MaxEC of the knee extensors (KE) first followed by the 30MaxEC of EF or 60MaxEC of KF using the ipsilateral (ipsi-EE-EF, ipsi-KE-KF) or contralateral limb (contra-EE-EF, contra-KE-KF). The two exercise bouts were separated by 2 wk for all groups. Changes in muscle damage markers before to 5 d after exercise were compared among the groups by mixed-design two-way ANOVA.
resultsChanges in the markers after the second bout of the ipsi-EE-EF, contra-EE-EF, ipsi-KE-KF, and contra-KE-KF groups were smaller ( P < 0.05) than those after the first bout of the contra-EF-EF and contra-KF-KF groups, respectively. The changes after the second bout were smaller ( P < 0.05) for the ipsi-EE-EF than contra-EE-EF, and ipsi-KE-KF than contra-KE-KF group; however, those in the contra-EE-EF and contra-KE-KF groups were larger ( P < 0.05) than those after the second bout of the contra-EF-EF and contra-KF-KF groups.
conclusionsThese results showed that the magnitude of muscle damage of EF or KF was reduced by the initial bout of EE or KE eccentric exercise performed by both ipsilateral and contralateral limbs, suggesting that muscle damage protective effect is conferred by the antagonist muscle in the same and opposite limbs.
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