ArticleJournal of psychopharmacology (Oxford, England)2025
Habitual caffeine intake, genetics and cognitive performance.
Article in Journal of psychopharmacology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Effects of Caffeine Ingestion on Morning Cognitive and Muscle Strength Measures in Males: A Standardized Approach.Nutrients · 2026Trial
- Acute Effects of Guarana (Sports (Basel, Switzerland) · 2026Article
- Association between daily coffee intake and diabetic kidney disease: evidence from the 2007 to 2016 NHANES.International urology and nephrology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResearch on caffeine and cognitive performance remains controversial. Variations in genes associated with caffeine metabolism and response such as
aimTo investigate caffeine × gene interactions on cognitive performance in all key domains of cognition in healthy individuals.
methodsParticipants completed a lifestyle and food frequency questionnaire and a cognitive test battery including validated tasks to assess the domains of social cognition, memory, attention and executive function. Genotyping was performed for
resultsSignificant gene × caffeine interactions were observed for the domains of social cognition, (
conclusionsThe present findings suggest an association between genetic caffeine metabolism, habitual caffeine intake and cognitive function in the domains of social cognition and executive function. More research in naturalistic environments using larger cohorts is needed to confirm these findings to add to our understanding of how habitual caffeine may influence cognitive function based on individual genotype.
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Registered trials
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