ArticleSpinal cord series and cases2024
Integration of functional electrical stimulation during robotic-assisted intervention to increase bone mineral density in individuals with complete spinal cord injury: case report.
Article in Spinal cord series and cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The effect of device-based neuromodulation on the motor recovery of patients with spinal cord injury.Spinal cord · 2025Pooled it
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionA spinal cord injury (SCI) leads to an alteration of the central nervous system which significantly impacts the health, function and quality of life of those affected. Since SCI leads to a loss lower limbs usage, sublesional osteoporosis is a common and established consequence with high risk of fracture in this population. The mechanical loading remains the most effective approach to stimulate physiologic bone remodeling. Furthermore, functional electrical stimulation, by producing active muscle contractions, would also increase bone mineral density. Combining functional electrical stimulation (FES) with mechanical stress during functional task such as walking or cycling would provide better results on BMD. CASE PRESENTATION: This case report describes a 64-years old man with a chronic complete SCI (T2-T3; AIS A) who was gradually exposed to mechanical stress (walking robot, standing, bicycle) coupled with FES for 26 months. Bone mineral density of the femoral head (BMDf) was defined at 3 different time points (baseline, after 10 and 26 months). The Fracture Risk Assessment Tool (FRAX) was used to calculate T-scores based on BMDf. Before the intervention, BMDf indicated severe osteoporosis in this man. After 10 months of combined intervention, the BMDf decreased to reach the level of osteopenia after 26 months. DISCUSSION: The implementation of an intervention combining weight-bearing during robotic-assisted walking and FES would improve bone mineral density and could reduce the risk of fracture in people with complete SCI.
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