Evidence map›Paper›PMID 39648070›Full record

ReviewSeminars in perinatology2025

Beyond a simple cause and effect relationship: Exploring the long-term outcomes of children prenatally exposed to opioids and other substances.

Ekaterina Burduli, Hendrée E Jones

Abstract readReview
In one paragraph

Review in Seminars in perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ekaterina BurduliWashington State University, College of Nursing, Spokane, WA, USA; Washington State University, Department of Community and Behavioral Health, Elson S. Floyd College of Medicine, Spokane, WA, USA.
Hendrée E JonesUniversity of North Carolina at Chapel Hill, UNC Horizons, Department of Obstetrics and Gynecology, Chapel Hill, NC, USA. Electronic address: hendree_jones@med.unc.edu.

Funding

Medically-supervised withdrawal vs. agonist maintenance in the treatment of pregnant women with opioid use disorder: Maternal, fetal, and neonatal outcomesR01DA047867 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HEIL, SARAH H, JONES, HENDREE E · 2018 to 2022
$3.3M
Effective Caregiving for Neonatal Abstinence Syndrome: Development of an Instructional Mobile Technology Platform for High-Risk Pregnant WomenK01DA051780 · NIDA · WASHINGTON STATE UNIVERSITY · PI BURDULI, EKATERINA · 2020 to 2024
$844k
NIDA NIH HHS K01 DA051780NIDA NIH HHS R01 DA047867
6 · The paper itself

Abstract

The long-term outcomes of children exposed to opioids and other substances in utero, specifically those diagnosed with Neonatal Abstinence Syndrome (NAS), present a complex interaction of different factors. First, NAS and its clinical presentation will be defined, then summarized will be an overview of NAS prevalence, recent trends, and significance of NAS in the context of the rising synthetic opioid and polysubstance use. Highlighted will also be the identified risk factors for NAS, especially regarding the role of environmental and psychosocial stressors during pregnancy. Finally, reviewed will be the existing NAS literature, including its gaps and limitations, and suggested recommendations for future research and policy considerations for improving care for children and families impacted by NAS.

Indexed as

Analgesics, OpioidNeonatal Abstinence SyndromeOpioid-Related DisordersPregnancy ComplicationsPrenatal Exposure Delayed EffectsChildFemaleHumansInfant, NewbornPregnancyPrevalenceRisk FactorsAnalgesics, OpioidChildNeonatal abstinence syndromeNeonatal opioid withdrawalOpioid usePerinatal, Long-term outcomesPregnancy

Identifiers

PMID39648070
PMCPMC11810605

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.