Evidence map›Paper›PMID 39647462›Full record

ReviewEpidemics2024

Serodynamics: A primer and synthetic review of methods for epidemiological inference using serological data.

James A Hay, Isobel Routledge, Saki Takahashi

Abstract readReview
In one paragraph

Review in Epidemics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Serological Evidence of WidespreadVeterinary sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James A HayPandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. Electronic address: james.hay@ndm.ox.ac.uk.
Isobel RoutledgeDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA. Electronic address: isobel.routledge@ucsf.edu.
Saki TakahashiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: saki.takahashi@jhu.edu.

Funding

Bill & Melinda Gates Foundation NV-060109Wellcome Trust
6 · The paper itself

Abstract

We present a review and primer of methods to understand epidemiological dynamics and identify past exposures from serological data, referred to as serodynamics. We discuss processing and interpreting serological data prior to fitting serodynamical models, and review approaches for estimating epidemiological trends and past exposures, ranging from serocatalytic models applied to binary serostatus data, to more complex models incorporating quantitative antibody measurements and immunological understanding. Although these methods are seemingly disparate, we demonstrate how they are derived within a common mathematical framework. Finally, we discuss key areas for methodological development to improve scientific discovery and public health insights in seroepidemiology.

Indexed as

HumansSeroepidemiologic StudiesInfectious disease modelingSerodynamicsSeroepidemiologySerology

Identifiers

PMID39647462
PMCPMC11649536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.