Evidence map›Paper›PMID 39645540›Full record

ArticleArchives of environmental contamination and toxicology2025

Comparison of Oxytetracycline and Sulfamethazine Effects Over Root Elongation in Selected Wild and Crop Plants Commonly Present in the Mediterranean Cropland and Pasture Scenarios.

Carlos Sacristán, Marta Guerrero, Sonia Sánchez, Antonio Rodríguez, Rosa María García, Ana Carolina Ewbank, Meritxell Gros, Sara Rodríguez-Mozaz, Isaura Martín Martínez, Luis Guasch and 1 more

Abstract readComparative Study
In one paragraph

Article in Archives of environmental contamination and toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlos SacristánGroup of Epidemiology and Environmental Health, Animal Health Research Centre (INIA-CISA/CSIC), Carretera Algete-El Casar de Talamanca, Km. 8,1, 28130, Valdeomos, Madrid, Spain.ORCID http://orcid.org/0000-0002-6111-6301
Marta GuerreroSpanish Plant Genetic Resources Centre (CRF) (INIA-CRF/CSIC), 28805, Alcalá de Henares, Madrid, Spain.ORCID http://orcid.org/0000-0002-4113-7973
Sonia SánchezSpanish Plant Genetic Resources Centre (CRF) (INIA-CRF/CSIC), 28805, Alcalá de Henares, Madrid, Spain.
Antonio RodríguezGroup of Epidemiology and Environmental Health, Animal Health Research Centre (INIA-CISA/CSIC), Carretera Algete-El Casar de Talamanca, Km. 8,1, 28130, Valdeomos, Madrid, Spain.
Rosa María GarcíaSpanish Plant Genetic Resources Centre (CRF) (INIA-CRF/CSIC), 28805, Alcalá de Henares, Madrid, Spain.
Ana Carolina EwbankGroup of Epidemiology and Environmental Health, Animal Health Research Centre (INIA-CISA/CSIC), Carretera Algete-El Casar de Talamanca, Km. 8,1, 28130, Valdeomos, Madrid, Spain. ewbank@inia.csic.es.ORCID http://orcid.org/0000-0002-5617-9287
Meritxell GrosCatalan Institute for Water Research (ICRA), C/ Emili Grahit 101, 17003, Girona, Spain.ORCID http://orcid.org/0000-0002-4365-5299
Sara Rodríguez-MozazUniversitat de Girona (UdG), 17004, Girona, Spain.ORCID http://orcid.org/0000-0003-2962-8144
Isaura Martín MartínezSpanish Plant Genetic Resources Centre (CRF) (INIA-CRF/CSIC), 28805, Alcalá de Henares, Madrid, Spain.
Luis GuaschSpanish Plant Genetic Resources Centre (CRF) (INIA-CRF/CSIC), 28805, Alcalá de Henares, Madrid, Spain.ORCID http://orcid.org/0000-0001-7117-767X
Ana de la TorreGroup of Epidemiology and Environmental Health, Animal Health Research Centre (INIA-CISA/CSIC), Carretera Algete-El Casar de Talamanca, Km. 8,1, 28130, Valdeomos, Madrid, Spain. torre@inia.csic.es.ORCID http://orcid.org/0000-0003-4560-5196

Funding

European Regional Development Fund MCI/AEI/FEDEREuropean Regional Development Fund UEGeneralitat de Catalunya SGR ICRA-ENV 2021 01282Juan de la Cierva JDC2022-048632-IJuan de la Cierva incorporación IJC2020-046019-IRamon y Cajal RYC2020-030324-ISpanish Ministry of Science, Innovation and Universities, the Spanish State Research Agency RTI2018_095586_B_C21
6 · The paper itself

Abstract

Fertilization with animal manure and sewage sludge, and the use of sewage water for irrigation, can lead to high antimicrobial concentrations in agricultural soils. Once in soil, antimicrobials can exert direct and indirect toxic effects on plants by misbalancing plant-microbe symbiotic relationships. We performed germination tests to determine the optimum germination conditions of 24 plant species (10 crop and 14 wild species). Subsequently, we analyzed the differences in oxytetracycline and sulfamethazine phytotoxicity in 19 plant species for which optimum germination conditions could be established. The root elongation of the majority of wild species was inhibited in the presence of oxytetracycline and sulfamethazine, whereas crops were mainly affected by oxytetracycline. There were no differences in sensitivity to oxytetracycline between crop and wild plant species, whereas wild plants were significantly more susceptible to sulfamethazine than crop species. Thus, to cover both productivity and biodiversity protection goals, we recommend pharmaceuticals' predicted no-effect concentration (PNEC) values based on crop and wild plant species phytotoxicity data.

Indexed as

Anti-Bacterial AgentsCrops, AgriculturalOxytetracyclinePlant RootsSoil PollutantsSulfamethazineGerminationAnti-Bacterial AgentsOxytetracyclineSoil PollutantsSulfamethazine

Identifiers

PMID39645540
PMCPMC11782457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.