Evidence map›Paper›PMID 39644756›Full record

ArticleArchives of gerontology and geriatrics2025

Do obstructive and restrictive pulmonary disorders increase the incidence risk of dynapenia in adults aged 50 and older?

Thales Batista de Souza, Roberta de Oliveira Máximo, Isabella Letícia de Pádua Cruz E Souza, Thaís Barros Pereira da Silva, Mariane Marques Luiz, Sara Souza Lima, Natália Cochar-Soares, Leticia Coelho Silveira, Valdete Regina Guandalini, Patrícia Silva Tofani and 3 more

Abstract read
In one paragraph

Article in Archives of gerontology and geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Thales Batista de SouzaPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Roberta de Oliveira MáximoPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Isabella Letícia de Pádua Cruz E SouzaPostgraduate programme in Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Thaís Barros Pereira da SilvaPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Mariane Marques LuizPostgraduate programme in Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Sara Souza LimaPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Natália Cochar-SoaresPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Leticia Coelho SilveiraPostgraduate programme in Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Valdete Regina GuandaliniPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Patrícia Silva TofaniPostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil.
Andrew SteptoeDepartment of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 7HB, United Kingdom.
Cesar de OliveiraDepartment of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 7HB, United Kingdom.
Tiago da Silva AlexandrePostgraduate programme in Gerontology, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil; Postgraduate programme in Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil; Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 7HB, United Kingdom; Gerontology Department, Federal University of Sao Carlos, Rodovia Washington Luís, km 235, SP-310, Sao Carlos, São Paulo, Brazil. Electronic address: tiagoalexandre@ufscar.br.

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
NIA NIH HHS R01 AG017644
6 · The paper itself

Abstract

objectiveThis study aims to evaluate whether obstructive or restrictive lung disorders are associated with the incidence of dynapenia in individuals aged 50 and over.

methodsLongitudinal study involving 4,975 participants from the English Longitudinal Study of Aging (ELSA) aged 50 or older, without dynapenia at baseline, followed for eight years. Lung function was assessed by spirometry (predicted percentage) and participants were classified as no pulmonary disorder (FEV

resultsThe incidence density of dynapenia was 14.2/1000 person-years (95 %CI 12.6-15.9) in those without pulmonary disorders, 25.1/1000 person-years (95 % CI 21.2-29.7) in those with restrictive pulmonary disorders and 36.6/1000 person-years (95 % CI 23.8-56.1) in those with obstructive pulmonary disorders. Having an obstructive pulmonary disorder increased the risk of developing dynapenia by 62 % (95 % CI 1.09-2.41), while having a restrictive pulmonary disorder increased the risk by 37 % (95 % CI 1.13-1.64).

conclusionObstructive and restrictive pulmonary disorders are risk factors for a higher incidence of dynapenia in individuals aged 50 years or older.

Indexed as

SpirometryAgedEnglandFemaleHand StrengthHumansIncidenceLongitudinal StudiesLung Diseases, ObstructiveMaleMiddle AgedRisk FactorsDynapeniaForced expiratory volumeForced vital capacityHandgrip strengthPulmonary function

Identifiers

PMID39644756
PMCPMC11717600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.