Evidence map›Paper›PMID 39644503›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Switchable Adhesion of Hydrogels to Plant and Animal Tissues.

Leah K Borden, Morine G Nader, Faraz A Burni, Samantha M Grasso, Irene Orueta-Ortega, Mahima Srivastava, Paula Montero-Atienza, Metecan Erdi, Sarah L Wright, Rajabrata Sarkar and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Switchable Adhesion of Hydrogels to Plant and Animal Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Leah K BordenDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Morine G NaderDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Faraz A BurniDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Samantha M GrassoDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Irene Orueta-OrtegaDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Mahima SrivastavaDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Paula Montero-AtienzaFischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Metecan ErdiDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.
Sarah L WrightSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, Washington DC, 20010, USA.
Rajabrata SarkarDivision of Vascular Surgery, University of Maryland, Baltimore, MD, 21201, USA.
Anthony D SandlerSheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, Washington DC, 20010, USA.
Srinivasa R RaghavanDepartment of Chemical & Biomolecular Engineering, University of Maryland, College Park, MD, 20742, USA.ORCID https://orcid.org/0000-0003-0710-9845

Funding

Clark Fellowship and subsequently a GAANN fellowshipTEDCO Maryland Innovation Initiative
6 · The paper itself

Abstract

The ability to "switch on" adhesion between a thin hydrogel and a biological tissue can be useful in biomedical applications such as surgery. One way to accomplish this is with an electric field, a phenomenon termed electroadhesion (EA). Here, it is shown that cationic gels can be adhered by EA to tissues across all of biology. This includes tissues from animals, including humans and other mammals; birds; fish; reptiles (e.g., lizards); amphibians (e.g., frogs), and invertebrates (e.g., shrimp, worms). Gels can also be adhered to soft tissues from plants, including fruit (e.g., plums) and vegetables (e.g; carrot). In all cases, EA is induced by a low electric field (DC, 10 V) applied for a short time (20 s). After the field is removed, the adhesion persists. The adhesion can also be reversed by applying the field with opposite polarity. In mammals, EA is strong for many tissues (e.g., arteries, muscles, and cornea), but not others (e.g., adipose, brain). Tissues with anisotropic structure show anisotropic adhesion strength by EA. The higher the concentration of anionic polymers in a tissue, the stronger its adhesion to cationic gels. This underscores that EA is mediated by the electrophoresis of chain segments across the gel-tissue interface.

Indexed as

HydrogelsAnimalsHumansPlantsHydrogelsAdhesion on demandadhesion strengthreversible adhesionsmart materialsTissue microstructure

Identifiers

PMID39644503
PMCPMC11792046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.