Evidence map›Paper›PMID 39644382›Full record

ArticleAnalytical and bioanalytical chemistry2025

Long-term dysregulation of plasma peptidome in mild and multiple COVID-19 recovered patients revealed by a novel efficient peptidomics workflow.

Zhijing Song, Chaoran Liu, Yaozhou Liu, Zheng Bian, Qing Sun, Ting He, Rong Su, Shengchun Huang, Ningbin Dai, Ke Li Zhao and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhijing SongKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Chaoran LiuKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Yaozhou LiuKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Zheng BianKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Qing SunKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Ting HeYu-Yue Pathology Scientific Research Center, Chongqing, 401329, China.
Rong SuDepartment of Laboratory Medicine, Foshan Hospital of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine, Foshan, 528000, China.
Shengchun HuangDepartment of Laboratory Medicine, Foshan Hospital of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine, Foshan, 528000, China.
Ningbin DaiSuzhou Center for Disease Prevention and Control, Suzhou, 215004, China.
Ke Li ZhaoWestern Institute of Health Data Science, Chongqing, 400050, China.
Yan LiKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Kai LiangKey Laboratory of Epigenetic Regulation and Intervention, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. Liangkai2019@ibp.ac.cn.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2022A1515110537Biological Resources Programme of Chinese Academy of Sciences KFJ-BRP-004Innovation Project of Science and Technology from Foshan City 2220001005517Key Research & Development Plan from the Chinese Ministry of Science and Technology 2022YFF0713003Mountain Climbing Plan from the Foshan Hospital of TCM 202000205Strategic Priority Research Program of Chinese Academy of Sciences XDB38010200
6 · The paper itself

Abstract

After recovering from COVID-19, many patients experience "long COVID" symptoms. Existing research has predominantly focused on moderate to severe cases, with limited studies examining mild cases and recurrent infections. The circulating low-molecular-weight (LMW) peptidome, involving lipid metabolism, coagulation, and immune pathways, is crucial for understanding COVID-19's long-term effects. We developed a peptidomics workflow utilizing solid-phase extraction with highly wrinkled GO-Fe

Indexed as

COVID-19PeptidesProteomicsFemaleHumansLipid MetabolismMaleMiddle AgedSARS-CoV-2Solid Phase ExtractionTandem Mass SpectrometryWorkflowPeptidesCirculating peptidomicsHWGO-FLong COVID assessmentMild and multiple infectionSolid-phase extraction

Identifiers

PMID39644382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.