Evidence map›Paper›PMID 39644184›Full record

ArticleAdipocyte2024

Defining the role of 2,2',4,4'-tetrabromodiphenyl ether in 3T3-L1 cellular differentiation by transcriptome sequencing analysis.

Zao-Ling Liu, Aerna Qiayimaerdan, Yong Fan, Shu-Rui Jiang, Zunire Tuerxuna, Meng-Lin Wang, Haiqiemuhan Abudureheman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Adipocyte, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zao-Ling LiuDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Aerna QiayimaerdanDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Yong FanDepartment of Endocrinology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Shu-Rui JiangDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Zunire TuerxunaDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Meng-Lin WangDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.
Haiqiemuhan AbudurehemanDepartment of Epidemiology & Health Statistics, School of public health, Xinjiang Medical University, Urumqi, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigates the effect of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on the differentiation of 3T3-L1 cells and its mechanism of action. These 3T3-L1 cells were induced to differentiate in vitro using methylisobutylxanthine, dexamethasone, and insulin conditions, then exposed to either 1% DMSO as a control group or varying concentrations of BDE-47 (2.5 μM, 7.5 μM, 12.5 μM, 18.75 μM, and 25 μM). Oil red O staining showed that the absorbance value of the BDE-47 exposure groups was higher than that of the control group (

Indexed as

3T3-L1 CellsCell DifferentiationHalogenated Diphenyl EthersAdipocytesAdipogenesisAnimalsGene Expression ProfilingMiceTranscriptome2,2',4,4'-tetrabromodiphenyl etherHalogenated Diphenyl Ethers3T3-L1adipogenesisBDE-47mitosistranscriptome sequencing

Identifiers

PMID39644184
PMCPMC11633175

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.