Evidence map›Paper›PMID 39644044›Full record

ReviewHematology. American Society of Hematology. Education Program2024

Newborn screening initiatives for sickle cell disease in Africa.

Obiageli E Nnodu, Chinwe Onyinye Okeke, Hezekiah Alkali Isa

Abstract readReview
In one paragraph

Review in Hematology. American Society of Hematology. Education Program, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Review
  7. Integrated Newborn Screening in Nigeria: The Way Forward, A Workshop Report.International journal of neonatal screening · 2026
    Article
  8. Advances and Gaps in Global Newborn Screening for Sickle Cell Disease.International journal of neonatal screening · 2026
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Obiageli E NnoduDepartment of Haematology and Blood Transfusion, University of Abuja, Abuja, Nigeria.
Chinwe Onyinye OkekeCentre of Excellence for Sickle Cell Disease Research and Training, University of Abuja, Abuja, Nigeria.
Hezekiah Alkali IsaDepartment of Haematology and Blood Transfusion, University of Abuja, Abuja, Nigeria.

Funding

mAnaging siCkle CELl disease through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE)U01HL168084 · NHLBI · NEW YORK UNIVERSITY · PI Obiageli Eunice Nnodu, EMMANUEL K PEPRAH · 2023 to 2026
$2.7M
Sickle Pan African Research Consortium NigEria (SPARC-NEt)U01HL156942 · NHLBI · UNIVERSITY OF ABUJA · PI NNODU, OBIAGELI EUNICE · 2021 to 2025
$1.3M
Sickle Pan Africa Research Consortium TRAINing (SPARC- TRAIN) ProgramD43TW012724 · FIC · UNIVERSITY OF ABUJA · PI Prisca Olabisi Adejumo, Obiageli Eunice Nnodu · 2024 to 2026
$694k
FIC NIH HHS 1D43TW012724-01FIC NIH HHS D43 TW012724NHLBI NIH HHS U01 HL156942NHLBI NIH HHS U01 HL168084NIH HHS 1UO1HL156942-4
6 · The paper itself

Abstract

Sickle cell disease (SCD) is a genetic blood disorder in high prevalence in sub-Saharan Africa (SSA) that leads to high morbidity and early mortality. Newborn screening (NBS) with evidence-based interventions saves lives of individuals with SCD. SSA accounts for 75% of the global prevalence of SCD, but it has not been able to implement universal NBS for SCD. This article examines policy framework for NBS in SSA; the methods, processes, barriers, and enablers of NBS; and enrollment in comprehensive care to make available the evidence-based interventions that caregivers need to access in order to save the lives of babies with SCD.

Indexed as

Anemia, Sickle CellNeonatal ScreeningAfricaAfrica South of the SaharaFemaleHumansInfant, Newborn

Identifiers

PMID39644044
PMCPMC11665715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.