ArticleBMC psychiatry2024
Sex differences in loneliness, social isolation, and their impact on psychiatric symptoms and cognitive functioning in schizophrenia.
Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Gender differences in working memory impairment and metabolic characteristics among patients with stable schizophrenia: a cross-sectional study.European archives of psychiatry and clinical neuroscience · 2026Article
- Loneliness is associated with cognitive impairment in patients with schizophrenia: the mediating roles of sleep quality and anxiety.European archives of psychiatry and clinical neuroscience · 2026Article
- Sex Differences in Schizophrenia Across the Reproductive Lifespan.Current psychiatry reports · 2026Review
- Loneliness as a sex-specific risk factor for cognitive aging.Frontiers in human neuroscience · 2026Review
- Loneliness and cognitive decline among U.S. adults: A stratified analysis of the BRFSS.PloS one · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundSocial isolation and loneliness, objective and subjective features of dysfunctional social relationships, are more prevalent in patients with schizophrenia (SCZ) than in the general population. This study aimed to explore sex differences in loneliness and social isolation among Chinese chronic SCZ patients, and to investigate their relationships with psychiatric symptoms and cognitive functioning.
methodsA total of 323 SCZ patients, comprising 136 males and 187 females, were recruited. Psychopathology, cognitive functioning, loneliness, social isolation were assessed using the Positive and Negative Syndrome Scale (PANSS), the Repeated Battery for Assessment of Neuropsychological Status (RBANS), the UCLA (University of California, Los Angeles) Loneliness Scale (Version 3) and the Social Isolation Index (ISI). Multiple linear regression models were conducted to test the independent, relative, and synergistic efects of loneliness and social isolation on psychiatric symptoms and cognitive performance for male and female patients separately.
resultsMale patients exhibited higher UCLA loneliness scale scores and social isolation scores compared to female patients (p
conclusionLoneliness and social isolation are more pronounced in male SCZ patients than in female patients. Both loneliness and social isolation are positively related to psychiatric symptoms in male patients, while loneliness is negatively associated with cognitive functioning in female patients.
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