ArticleInternational urology and nephrology2025
A potential therapeutic strategy using a miniature, implantable, wireless nerve stimulation device for treating stress urinary incontinence in rats.
Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.Nature communications · 2026Article
- Effects of pelvic floor electrical stimulation with an implantable device at different frequencies on stress urinary incontinence in rats.European journal of medical research · 2025Article
- Implantable electrical stimulation device enhances pelvic floor tissue repair and reduces collagen over-degradation in rats with stress urinary incontinence.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeThe present study examined the effects of a miniature, implantable, wireless stimulation device for treating stress urinary incontinence (SUI) in rats.
methodsTwenty-four female Sprague-Dawley rats were randomly assigned to three groups: Group 1 (Control), Group 2 (Sham), and Group 3 (Stimulation). All animals underwent vaginal distension (VD) to mimic postpartum SUI. Groups 2 and 3 were implanted with a stimulator in the pelvic floor muscle, but only Group 3 received continuous stimulation for two weeks. Multiple cystometrograms (CMGs) were performed to determine the leak point pressure (LPP) and maximal bladder capacity (MBC).
resultsIn the rat model, LPP in Group 1 after VD and after two weeks decreased significantly from baseline (21.1 ± 2.5 and 30.8 ± 5.2 vs. 52.5 ± 6.3 cmH
conclusionsThe current study demonstrated the effectiveness of the implantable stimulation device for treating SUI in a rat model. Further studies are needed to determine its long-term safety and action mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.