Evidence map›Paper›PMID 39643837›Full record

ArticleWorld journal of urology2024

Novel small fragment removal system may improve extraction of renal calculi: an in vitro study.

John Lazarus, Mark Wellman, Jørgen Wulfsberg, Tommaso Ceccato, Jeff John

Abstract read
In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John LazarusDivision of Urology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. j.lazarus@uct.ac.za.
Mark WellmanDivision of Urology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Jørgen WulfsbergFaculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Tommaso CeccatoDepartment of Surgery, Oncology, Gastroenterology and Urological Unit, University of Padova, Padova, Italy.
Jeff JohnDivision of Urology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe a novel Small Fragment Removal System (SFRS) which is hypothesized to improve stone fragment removal during flexible ureteroscopy in patients with urolithiasis. The SFRS consists of three parts: a Syphon Ureteric Access Sheath (SUAS), a Dual Action Pump (DAP) and an Agitator. This bench assessment aims to assess the SFRS's impact on intra-renal pressure (IRP), irrigant flow rate and stone fragment removal compared to a traditional UAS. MATERIALS AND

methodsA validated phantom kidney and fibre optic pressure sensor was used to assess IRP. Standardized irrigation via a flexible ureterorenoscope was instilled through a traditional UAS and compared to the novel SFRS. Both were 11/13Fr in size. Measured minute volume, IRP and percentage of stone fragments removed were compared.

resultsThe mean IRP using a traditional UAS and SFRS was 24,3mmHg and 9,4mmHg respectively. The flow rate of the traditional UAS was 25mL/min, compared to 31mL/min with the SFRS attached. During bolus fluid administration using the traditional UAS the maximum IRP increased to 41mmHg, compared to 9,3mmHg with the SFRS attached. A mean of 42,7% (0,103 g of 0,305 g) of weighed dry stones were removed with the traditional UAS compared to 77,6% (0,233 g of 0,299 g) with the SFRS attached, p = 0,017.

conclusionsThe described Small Fragment Removal System (SFRS) is different from traditional UASs by incorporating a syphoning mechanism. In addition, it has a Dual Action Pump which both boluses and augments the aspiration of irrigant by the Syphon. It further includes a deflectable Agitator to flush out stone fragments.

Indexed as

Equipment DesignKidney CalculiUreteroscopyHumansIn Vitro TechniquesEndourologyIntrarenal pressureRenal calculiUreteral access sheathUreterorenoscopy

Identifiers

PMID39643837
PMCPMC11624219

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.