Evidence map›Paper›PMID 39643817›Full record

ArticleBiogerontology2024

Association of serum metabolites with frailty phenotype and its components: a cross-sectional case-control study.

Takashi Shida, Sho Hatanaka, Narumi Kojima, Takahisa Ohta, Yosuke Osuka, Kazushi Maruo, Hiroyuki Sasai

Abstract read
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In one paragraph

Article in Biogerontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takashi ShidaResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan. t_shida@tmig.or.jp.ORCID 0000-0002-9788-2411
Sho HatanakaResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID 0009-0002-8728-5071
Narumi KojimaResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID 0000-0001-5742-0389
Takahisa OhtaResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID 0000-0003-0092-6543
Yosuke OsukaDepartment of Frailty Research, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.ORCID 0000-0002-5744-1961
Kazushi MaruoDepartment of Biostatistics, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.ORCID 0000-0002-3093-0386
Hiroyuki SasaiResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.ORCID 0000-0001-8120-6163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New insights into the metabolic mechanisms of frailty are needed. This study aimed to identify serum metabolites linked to frailty phenotype and its component through gas chromatography-mass spectrometry metabolomic analysis among community-dwelling older individuals. An exploratory, cross-sectional case-control study. Setting and participants: The participants were recruited from the ''Otassha Study,'' a cohort study conducted in Itabashi Ward, Tokyo, targeting women aged 65 years and older. The study population included 39 frail and 76 robust individuals. Metabolomic analysis was performed using the GCMS-TQ

Indexed as

Frail ElderlyFrailtyPhenotypeAgedAged, 80 and overBiomarkersCase-Control StudiesCross-Sectional StudiesFemaleGas Chromatography-Mass SpectrometryHumansMetabolomeMetabolomicsBiomarkersAgingFrailtyMetabolomicOlder adults

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.