Evidence map›Paper›PMID 39643724›Full record

ArticleMikrochimica acta2024

Development of a colorimetric/fluorescence dual-mode immunoassay for aflatoxin B1 based on streptavidin-induced gold nanoparticle aggregation.

Yaqian Cheng, Chenxi Wang, Xueyu Chang, Xuexia Jia, Zesheng Liu, Baolin Liu, Zhixian Gao, Huanying Zhou

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yaqian Cheng *Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China.
Chenxi Wang *Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China.
Xueyu ChangTianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China.
Xuexia JiaTianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China.
Zesheng LiuTianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China.
Baolin LiuSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China. blliuk@163.com.
Zhixian GaoTianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China. gaozhx@163.com.
Huanying ZhouTianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety, Military Medical Sciences Academy, Academy of Military Science, Tianjin, 300050, China. zhouhytj@163.com.

Funding

Guangdong Key Research and Development Program 2019B020211001Tianjin Natural Science Foundation 20JCQNJC00860
6 · The paper itself

Abstract

A dual-mode immunoassay method was developed for colorimetric and fluorescence detection of aflatoxin B1 (AFB1) based on streptavidin-induced gold nanoparticle aggregation (AuNP@SA). AuNP-modified streptavidin-biotin labeling AFB1 complete antigen aggregations (AuNP@SA@Bio-BSA-AFB1) were synthesized as the competitive binding and dual-mode probe. AuNP@SA@Bio-BSA-AFB1 aggregations possessed high colorimetric and fluorescence quenching intensities. AFB1 antibodies modified immunomagnetic microspheres were used as the capture probe. The competitive binding between AFB1 and AuNP@SA@Bio-BSA-AFB1 leads to changes in color and fluorescence intensity. The detection limit of the colorimetric method is 6.95 ng·mL

Indexed as

Aflatoxin B1ArachisColorimetryGoldLimit of DetectionMetal NanoparticlesStreptavidinAntibodies, ImmobilizedBiotinFood ContaminationImmunoassaySpectrometry, FluorescenceAflatoxin B1Antibodies, ImmobilizedBiotinGoldStreptavidinAuNPs; Aflatoxin B1Colorimetric detectionDual-mode methodFluorescence detection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.