Evidence map›Paper›PMID 39643573›Full record

ArticleVaccine2025

Sex differences in parental reasons for lack of intent to initiate HPV vaccination among adolescents ages 13-17 years: National Immunization Survey - Teen 2019-2021.

Erika Escabí-Wojna, Paola M Alvelo-Fernández, Erick Suárez, Vivian Colón-López

Abstract read
In one paragraph

Article in Vaccine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erika Escabí-WojnaDepartment of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico. Electronic address: erika.escabi@upr.edu.
Paola M Alvelo-FernándezDepartment of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico. Electronic address: paola.alvelo@upr.edu.
Erick SuárezDepartment of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico. Electronic address: erick.suarez@upr.edu.
Vivian Colón-LópezDepartment of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico. Electronic address: vivian.colon@upr.edu.

Funding

Implementation of School-Entry Policies for Human Papillomavirus VaccinationR01CA232743 · NCI · COMPREHENSIVE CANCER CENTER/ UNIV/PR · PI COLON, VIVIAN · 2019 to 2023
$1.9M
NCI NIH HHS R01 CA232743
6 · The paper itself

Abstract

backgroundThis study aimed to evaluate parents' main reasons for lack of intent to vaccinate their adolescent against human papillomavirus (HPV) from 2019 to 2021 and to examine changes in these main reasons stratified by sex of the adolescent.

methodsNIS-Teen data from 2019 to 2021 were used. Parents who had not vaccinated their adolescent aged 13-17 against HPV and had no intent to do so in the next 12 months were asked the main reason behind this decision. Reasons were grouped into eight domains. A multinomial logistic regression model stratified by sex was used to assess changes in the likelihood of each domain for 2020 and 2021 in comparison to 2019.

resultsA significant interaction between the reasons for lack of intent to vaccinate against HPV and year by sex was documented (p < 0.001). For males, the odds of parents reporting vaccine misinformation (ORadj: 1.30, 95 % CI: 1.26, 1.35), safety and effectiveness concerns (ORadj: 1.08, 95 % CI: 1.05, 1.12), systemic barriers (ORadj: 2.57, 95 % CI: 2.48, 2.66), lack of knowledge (ORadj: 1.44, 95 % CI: 1.39, 1.49), sociocultural barriers (ORadj: 3.20, 95 % CI: 3.09, 3.32), already UTD (ORadj: 2.48, 95 % CI: 2.39, 2.56), and handicapped/special needs/illness (ORadj: 1.88, 95 % CI: 1.79, 1.97), were significantly higher in 2021 compared to 2019. Whereas for females, the odds of reporting all domains were significantly lower in 2021 compared to 2019.

conclusionThe main domain reported was vaccine misinformation. Parents of males were more likely to report all domains in 2021 compared to 2019, the inverse of females. These can be addressed through public health interventions such as launching media campaigns to combat vaccine misinformation tailored to parents of male adolescents.

Indexed as

IntentionPapillomavirus InfectionsPapillomavirus VaccinesParentsVaccinationAdolescentFemaleHealth Knowledge, Attitudes, PracticeHumansMalePatient Acceptance of Health CareSex FactorsSurveys and QuestionnairesVaccination HesitancyPapillomavirus VaccinesHPV vaccineNIS-TeenVaccine hesitancy

Identifiers

PMID39643573
PMCPMC12053536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.