Evidence map›Paper›PMID 39643445›Full record

ArticleRNA (New York, N.Y.)2025

An MST-based assay reveals new binding preferences of IFIT1 for canonically and noncanonically capped RNAs.

Tomasz Spiewla, Katarzyna Grab, Anais Depaix, Kamil Ziemkiewicz, Marcin Warminski, Jacek Jemielity, Joanna Kowalska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tomasz SpiewlaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.ORCID 0000-0002-6542-3966
Katarzyna GrabDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.ORCID 0000-0001-8294-2808
Anais DepaixCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0003-1472-4985
Kamil ZiemkiewiczDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.ORCID 0000-0003-4301-8588
Marcin WarminskiDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.ORCID 0000-0002-1071-3405
Jacek JemielityCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0001-7633-788X
Joanna KowalskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland jkowalska@fuw.edu.pl.ORCID 0000-0002-9174-7999

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IFITs (interferon-induced proteins with tetratricopeptide repeats) are components of the innate immune response that bind to viral and cellular RNA targets to inhibit translation and replication. The RNA target recognition is guided by molecular patterns, particularly at the RNA 5' ends. IFIT1 preferably binds RNAs modified with the m

Indexed as

Adaptor Proteins, Signal TransducingCarrier ProteinsRNA-Binding ProteinsRNA CapsHumansProtein BindingAdaptor Proteins, Signal TransducingCarrier ProteinsIFIT1 protein, humanRNA-Binding ProteinsRNA Capsaffinitybinding assayIFIT1microscale thermophoresisRNA cap

Identifiers

PMID39643445
PMCPMC11789485

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.