Trial reportJournal of psychiatric research2025
Randomized controlled trial of computerized working memory training for Veterans with PTSD.
Trial report in Journal of psychiatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Limited and inconclusive effects of computer-based neurocognitive training on PTSD, comorbid depression and executive functioning: a systematic review and meta-analysis.Frontiers in psychology · 2025Pooled it
- Network-level structural alterations distinguish persistent from remitted post-traumatic stress disorder: a morphometric covariance approach.European journal of psychotraumatology · 2026Article
- The association between childhood maltreatment and neural functioning during a working memory task in adults with internalizing disorders.Brain imaging and behavior · 2026Article
- Combining trauma therapy with computer-based neurocognitive training in soldiers with post-traumatic stress disorder: a quasi-experimental study on symptom reduction and long-term memory functions.Frontiers in psychiatry · 2026Article
- Involvement of Matrix Metalloproteinases (MMP-2 and MMP-9), Inflammasome NLRP3, and Gamma-Aminobutyric Acid (GABA) Pathway in Cellular Mechanisms of Neuroinflammation in PTSD.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Posttraumatic stress disorder (PTSD) is a common psychiatric condition among Veterans that is associated with deficits across a range of neuropsychological domains including working memory. While gold-standard psychosocial treatments are highly effective, there still remains a high rate of individuals who do not engage with or fully benefit from them. Cognitive training targeting specific working memory deficits in PTSD presents an alternative treatment approach that has shown promise for reducing re-experiencing symptoms. The current study evaluated a 16-session working memory training (WMT) program in Veterans with PTSD, focusing on two levels of interference control training. Feasibility, acceptability, and clinical efficacy were assessed. Results indicated that the intervention was generally feasible and acceptable to Veterans and revealed similar effects between groups in the intent to treat analyses; however, the high interference control training group yielded greater re-experiencing symptom reductions than the low interference control training group among individuals who were protocol adherent (Hedges' g = 0.57). There were significant reductions in overall PTSD severity across groups. Results are broadly consistent with theoretical models and prior clinical trials linking working memory task improvement to re-experiencing symptom reductions. These results point to the potential for working memory training to be a viable intervention for PTSD in Veterans, though further research is necessary for validation and exploration of broader clinical outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.