Evidence map›Paper›PMID 39642220›Full record

ArticleScience advances2024

Dynamic silicone hydrogel gauze coatings with dual anti-blood adhesion mechanism for rapid hemostasis and minimal secondary damage.

Xiubin Xu, Yanting Chen, Yunlong Li, Xin Li, Jian Bai, Xusheng Jiang, Danfeng Yu, Xu Wu, Xi Yao

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiubin XuSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.ORCID 0000-0002-8571-4576
Yanting ChenSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.ORCID 0009-0006-4213-3524
Yunlong LiSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.
Xin LiDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-6843-4575
Jian BaiSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.
Xusheng JiangSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.
Danfeng YuSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.ORCID 0000-0002-5558-2832
Xu WuSchool of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, China.ORCID 0000-0002-8907-6073
Xi YaoDepartment of Biomedical Sciences, City University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-8986-3571

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemostatic materials that can rapidly control bleeding without causing secondary damage or sharp pain upon removal are receiving increasing demands in acute trauma treatments and first-aid supplies. Here, we report the development of a dynamic silicone hydrogel coating on medical gauze to enable rapid hemostasis and synergistic anti-blood adhesion properties. The silicone hydrogel can spontaneously form oriented cross-linked structures on fibrous medical gauze through a solution-processing method to achieve macroscopic superhydrophobicity with microscopic surface slipperiness, resulting in excellent anti-blood adhesion with the on-wound peeling force at ~0 millinewton. The development of dynamic silicone hydrogel coating on medical gauze enables a unique integration of advanced features including instant bleeding control, excellent anti-blood adhesion, and excellent air permeability. The proposed strategy is also suitable for scalable production, making it promising in the applications of trauma management.

Indexed as

HemostasisHydrogelsSiliconesAnimalsBandagesCoated Materials, BiocompatibleHemorrhageHemostaticsHumansCoated Materials, BiocompatibleHemostaticsHydrogelsSilicones

Identifiers

PMID39642220
PMCPMC11623298

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.