Evidence map›Paper›PMID 39642200›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins.

Miao Yu, Andrey Yu Gruzinov, Hao Ruan, Tom Scheidt, Aritra Chowdhury, Sabrina Giofrè, Ahmed S A Mohammed, Joana Caria, Paul F Sauter, Dmitri I Svergun and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Intrinsic stiffness andPNAS nexus · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miao Yu *Biocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.ORCID 0000-0002-5890-9204
Andrey Yu Gruzinov *BIOSAXS Group, European Molecular Biology Laboratory, Hamburg Unit, Hamburg 22607, Germany.
Hao Ruan *Biocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.
Tom Scheidt *Biocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.ORCID 0000-0002-0185-7730
Aritra ChowdhuryStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.ORCID 0000-0002-0579-292X
Sabrina GiofrèBiocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.
Ahmed S A MohammedBIOSAXS Group, European Molecular Biology Laboratory, Hamburg Unit, Hamburg 22607, Germany.ORCID 0000-0002-6603-6642
Joana CariaBiocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.
Paul F SauterStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.
Dmitri I SvergunBIOSAXS Group, European Molecular Biology Laboratory, Hamburg Unit, Hamburg 22607, Germany.
Edward A LemkeBiocenter, Johannes Gutenberg University Mainz, Mainz 55128, Germany.ORCID 0000-0002-0634-0503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrinsically disordered proteins (IDPs) adopt ensembles of rapidly fluctuating heterogeneous conformations, influencing their binding capabilities and supramolecular transitions. The primary conformational descriptors for understanding IDP ensembles-the radius of gyration (

Indexed as

Fluorescence Resonance Energy TransferIntrinsically Disordered ProteinsScattering, Small AngleX-Ray DiffractionModels, MolecularProtein ConformationIntrinsically Disordered Proteinsanomalous SAXSdistance rulerFRETintrinsically disordered proteinstructural biology

Identifiers

PMID39642200
PMCPMC11648921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.