Evidence map›Paper›PMID 39642020›Full record

Observational studyJournal of acquired immune deficiency syndromes (1999)2025

HIV Pre-exposure Prophylaxis Use Among Men Experiencing Incarceration in the United States: A Prospective Cohort Study.

Matthew Murphy, Brooke Rogers, Drew Galipeau, Emily Toma, Alexi Almonte, Siena Napoleon, Christopher H Schmid, Jasjit S Ahluwalia, Philip Chan

Abstract readObservational Study
In one paragraph

Observational study in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Infection Control in Carceral Facilities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew MurphyWarren Alpert School of Medicine, Brown University, Providence, RI.ORCID 0000-0002-0024-4668
Brooke RogersWarren Alpert School of Medicine, Brown University, Providence, RI.
Drew GalipeauThe Miriam Hospital, The Lifespan Healthcare System, Providence, RI.
Emily TomaBrown University School of Public Health, Providence, RI.
Alexi AlmonteThe Miriam Hospital, The Lifespan Healthcare System, Providence, RI.
Siena NapoleonBrown University School of Public Health, Providence, RI.
Christopher H SchmidBrown University School of Public Health, Providence, RI.
Jasjit S AhluwaliaWarren Alpert School of Medicine, Brown University, Providence, RI.
Philip ChanWarren Alpert School of Medicine, Brown University, Providence, RI.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI ROUNDS, SHARON IRENE SMITH · 2016 to 2025
$45.0M
Using wearables and EMA to examine the links between cannabis and depressionP20GM130414 · NIGMS · BROWN UNIVERSITY · PI Tyler Blake Wray · 2019 to 2026
$22.0M
An intervention to improve HIV pre-exposure prophylaxis initiation, adherence and linkage to care for recently incarcerated men who inject drugs.K23DA054003 · NIDA · RHODE ISLAND HOSPITAL · PI Matthew Murphy · 2022 to 2026
$977k
Gilead Sciences IN-US-276-5463National Institute of Allergy and Infectious Diseases P30AI042853NIAID NIH HHS P30 AI042853NIDA NIH HHS 1K23DA054003-01A1NIDA NIH HHS K23 DA054003NIDA NIH HHS L30 DA052067NIGMS NIH HHS P20 GM130414NIGMS NIH HHS P20GM130414NIGMS NIH HHS U54 GM115677
6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) is an effective approach to preventing HIV acquisition and recommended for populations over-represented in carceral systems, given the overlap with populations disproportionately impacted by HIV. However, few studies have focused on PrEP initiation outcomes in a carceral setting to maximize public health impact.

settingThis study was conducted in a unified jail/prison system within the state of Rhode Island located in the United States.

methodsA prospective observational cohort of men initiating PrEP within a jail setting was enrolled in this trial. Men were referred by providers, staff, or after self-presenting for HIV preventive care, these individuals were offered enrollment in the study that involved evaluation for clinical PrEP eligibility, PrEP initiation while incarcerated, continuation upon community re-entry, and linkage to a community PrEP provider after release.

resultsA total of 100 men in the jail facility (eg, "intake") were enrolled in the cohort. Of the 100 men enrolled, 83% were determined to be PrEP eligible through standard clinical evaluation, 37% were prescribed PrEP, and 26% initiated PrEP while incarcerated. In total, 5% of enrolled individuals were linked successfully to PrEP care in the community.

conclusionOur findings suggest preliminary feasibility and acceptability of initiating PrEP within a jail setting. There were significant challenges across the PrEP care continuum that can be used to inform future studies and practice.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisPrisonersAdultHumansIncarcerationMaleMiddle AgedPrisonsProspective StudiesRhode IslandUnited StatesYoung AdultAnti-HIV Agents

Identifiers

PMID39642020
PMCPMC11624426

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.