ArticleEnvironmental health perspectives2024
Association of Tailpipe-Related and Nontailpipe-Related Air Pollution Exposure with Cognitive Decline in the Chicago Health and Aging Project.
Article in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- The Human Microbiome in Airborne Particulate Matter-Associated Aging-Related Chronic Diseases: An Evidence-Stratified Review.Environment & health (Washington, D.C.) · 2026Review
- Residential aircraft and road noise exposure, cognition, and Alzheimer's dementia in a US cohort of older adults.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Long-term exposure to air pollution and cognitive aging: Findings from a United States cohort of older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Alzheimer's Disease in Illinois: Analyzing Disparities and Projected Trends.Geriatrics (Basel, Switzerland) · 2025Review
- Association of tailpipe-related and nontailpipe-related air pollution exposure with neuroimaging outcomes.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Intercomparison of Modeled Urban-Scale Vehicle NOEnvironmental science & technology · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundEvidence suggests that long-term exposure to air pollution may increase the risk of dementia and related cognitive outcomes. A major source of air pollution is automotive traffic, which is modifiable by technological and regulatory interventions.
objectivesWe examined associations of four traffic-related air pollutants with rates of cognitive decline in a cohort of older adults.
methodsWe analyzed data from the Chicago Health and Aging Project (CHAP), a longitudinal (1993-2012) community-based cohort study of older adults that included repeated assessments of participants' cognitive performance. Leveraging previously developed air pollution models, we predicted participant-level exposures to the tailpipe pollutants oxides of nitrogen (
resultsUsing data from 6,061 participants, estimated associations of these pollutant exposures with cognitive decline were largely inconsistent with large adverse effects. For example, a standard deviation ( DISCUSSION: In this large prospective cohort study, we did not observe compelling evidence that long-term TRAP exposure is associated with cognitive decline. https://doi.org/10.1289/EHP14585.
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