Evidence map›Paper›PMID 39641877›Full record

ArticleStem cell reviews and reports2025

Alveolar Bone Tissue Engineering Using Deciduous Dental Pulp Stem Cells in a Patient with Cleft Lip and Palate.

Isabella Fernandes Carvalho, Brenda Santos Veloso, José Ferreira da Cunha Filho, Samara Kelly da Silva Cavalcante, Milena Regia Sousa Ferreira, Maysa Luna de Souza, Daniela Franco Bueno

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Stem cell reviews and reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isabella Fernandes CarvalhoCentro Universitário Christus - UNICHRISTUS, Rua João Adolfo Gurgel, 133, Cocó, Fortaleza, Ceará, ZC-60190-180, Brazil. draisabellacarvalho@gmail.com.ORCID 0000-0002-2909-4720
Brenda Santos VelosoCentro Universitário Christus - UNICHRISTUS, Rua João Adolfo Gurgel, 133, Cocó, Fortaleza, Ceará, ZC-60190-180, Brazil.ORCID 0009-0001-0591-355X
José Ferreira da Cunha FilhoHospital Infantil Albert Sabin, Fortaleza, Ceará, Brazil.ORCID 0000-0002-5780-7185
Samara Kelly da Silva CavalcanteCentro Universitário Christus - UNICHRISTUS, Rua João Adolfo Gurgel, 133, Cocó, Fortaleza, Ceará, ZC-60190-180, Brazil.ORCID 0000-0002-9799-8959
Milena Regia Sousa FerreiraCentro Universitário Christus - UNICHRISTUS, Rua João Adolfo Gurgel, 133, Cocó, Fortaleza, Ceará, ZC-60190-180, Brazil.ORCID 0009-0006-7286-3157
Maysa Luna de SouzaCentro Universitário Christus - UNICHRISTUS, Rua João Adolfo Gurgel, 133, Cocó, Fortaleza, Ceará, ZC-60190-180, Brazil.ORCID 0009-0003-4695-6606
Daniela Franco BuenoFaculdade Israelita de Ciencias da Saúde Albert Einstein (FICSAE), São Paulo, Brazil.ORCID 0000-0001-5932-6134

Funding

Programa de Apoio ao Desenvolvimento Institucional do Sistema Único de Saúde Programa de Apoio ao Desenvolvimento Institucional do Sistema Único de Saúde
6 · The paper itself

Abstract

The use of tissue bioengineering strategies in dentistry has gained relevance. Many studies indicate that stem cells associated with biomaterials can regenerate intraoral tissues and have been applied to patients with cleft lip and palate (CLP). One of the treatments is alveolar bone reconstruction through bone grafts, where the bone is removed from the donor site and placed in the alveolar cleft. The use of stem cells from deciduous dental pulp, associated with a hydroxyapatite and collagen scaffold, can eliminate the need for autologous bone grafts, reducing pain and morbidity at the donor site. This study presents a case report in which a patient with cleft lip and palate was treated using this technique, resulting in complete filling of the alveolar cleft after 12 months.

Indexed as

Alveolar ProcessCleft LipCleft PalateDental PulpStem CellsStem Cell TransplantationTissue EngineeringHumansTissue ScaffoldsTooth, DeciduousBioengineeringCleft lip and palateDentistryStem cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.