Evidence map›Paper›PMID 39641173›Full record

ReviewPediatric transplantation2025

Bridging the Gap: A Review of Pediatric to Adult Transition of Care in Liver Transplantation.

Beverly Kosmach-Park, Bethany Coyne, Nitika Gupta, George Mazariegos

Abstract readReview
In one paragraph

Review in Pediatric transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Advances in liver transplantation technology].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Beverly Kosmach-ParkDepartment of Transplant Surgery, UPMC Children's Hospital, Pittsburgh, Pennsylvania, USA.ORCID 0009-0005-1689-2669
Bethany CoyneDepartment of Family, Community and Mental Health Systems, University of Virginia School of Nursing, Charlottesville, Virginia, USA.
Nitika GuptaDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-6171-4731
George MazariegosDepartment of Transplant Surgery, UPMC Children's Hospital, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2624-8632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith improvements in long-term graft function and survival, an increasing population of pediatric liver transplant (LT) recipients now require adult care. A process to successfully transition young adults to adult LT centers is supported in the literature with discussions on the rationale for health care transition (HCT), barriers to transition, stakeholder perspectives, and transfer readiness (TR). Results of outcomes studies are difficult to generalize and there remains no standard of care for HCT in LT. Of concern is that the youth's increasing independence occurs during a period of developmental vulnerability, with a threat to graft function due to risk-taking behaviors, specifically nonadherence, that may lead to rejection, graft loss, and death. OBJECTIVES/

methodThe purpose of this comprehensive literature review is to discuss current knowledge, practices, and outcomes of HCT for LT recipients with additional support from literature in solid organ transplant (SOT) and pediatric-onset chronic conditions literature.

resultsRecent position statements in LT and SOT express a greater awareness of the importance of HCT with broad agreement that reflects a similarity in approach in endorsing HCT as an essential process that should be initiated in early adolescence with TR as a primary determinant of transfer; however, standardization with consistent outcomes measurement is lacking. The literature supports transition as an esential component of care that should be initated in early adolescence with programs that address knowlege, skill-development, and advocacy. The engagement of all stakeholders in LT is essential to program development.

conclusionsThere is increasing awareness among the multidisciplinary team of the importance and role of the adult provider in extending transitional care into the adult setting as executive functioning skills mature. Outcome measures need to be clearly defined and standardized. Regulatory agency involvement to validate and support the need for TOC programs is crucial and should promote outcomes research for best practice program standardization.

Indexed as

Liver TransplantationTransition to Adult CareAdolescentAdultChildHumansYoung Adultadherenceadolescencepediatric liver transplanttransition

Identifiers

PMID39641173
PMCPMC11622001

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.