Evidence map›Paper›PMID 39640848›Full record

ReviewFrontiers in molecular biosciences2024

Bacteriophage RNA polymerases: catalysts for mRNA vaccines and therapeutics.

Adithya Nair, Zoltán Kis

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. IntegratedMolecular therapy. Nucleic acids · 2026
    Article
  2. Revisiting the life cycle of temperate phages.Nature reviews. Microbiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. The TIGER/Islander resource for genomic islands.Microbiology resource announcements · 2025
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adithya NairSchool of Chemical, Materials and Biological Engineering, University of Sheffield, Sheffield, United Kingdom.
Zoltán KisSchool of Chemical, Materials and Biological Engineering, University of Sheffield, Sheffield, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Decades of research on bacteriophage-derived RNA polymerases (RNAPs) were vital for synthesizing mRNA using the

Indexed as

bacteriophage RNA polymerasein vitro transcriptionmRNA manufacturingmRNA vaccines and therapeuticsquality by designRNA polymerase engineeringT7 RNA polymeraseT7 RNA polymerase mutants

Identifiers

PMID39640848
PMCPMC11617373

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.