Evidence map›Paper›PMID 39640678›Full record

ArticleHeliyon2024

Fusobacterium in oral bacterial flora relates with asymptomatic brain lesions.

Yoshie Kato, Masahiro Takamura, Koichiro Wada, Haruki Usuda, Satoshi Abe, Shingo Mitaki, Atsushi Nagai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshie KatoDepartment of Neurology, Shimane University Faculty of Medicine, Japan.
Masahiro TakamuraDepartment of Neurology, Shimane University Faculty of Medicine, Japan.
Koichiro WadaDepartment of Pharmacology, Shimane University Faculty of Medicine, Japan.
Haruki UsudaDepartment of Pharmacology, Shimane University Faculty of Medicine, Japan.
Satoshi AbeDepartment of Neurology, Shimane University Faculty of Medicine, Japan.
Shingo MitakiDepartment of Neurology, Shimane University Faculty of Medicine, Japan.
Atsushi NagaiDepartment of Neurology, Shimane University Faculty of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Specific bacterial species in the oral cavity contribute to cerebral hemorrhage and microbleeds. The relationship between oral bacterial flora and asymptomatic brain lesions (ABL) remains unclear. This study aimed to investigate this relationship in a healthy Japanese cohort. Methods: This cross-sectional study included participants who underwent health examinations at our Brain Dock facility between October 2020 and March 2021. The oral microbiomes of participants with and without ABL were compared using magnetic resonance imaging. To extensively assess the oral bacterial flora, the differences in genes and species compositions between the ABL and noBL (without brain lesions) groups were statistically evaluated via extensive analysis using 16S rRNA gene-based cloning. Results: Among 143 patients, 48.3 % had ABL. In the univariate analyses, Conclusions: The elevation of

Indexed as

Asymptomatic brain lesionsFusobacterium nucleatumOral bacterial floraRisk factor

Identifiers

PMID39640678
PMCPMC11620239

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.