Evidence map›Paper›PMID 39640572›Full record

ArticleiScience2024

Immunogenic peptides putatively from intratumor microbes: Opportunities for colorectal cancer treatment.

Xiangyu Guan, Fanyu Bu, Yunyun Fu, Haibo Zhang, Haitao Xiang, Xinle Chen, Tai Chen, Xiaojian Wu, Kui Wu, Longqi Liu and 1 more

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiangyu GuanCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Fanyu BuBGI Research, Hangzhou 310030, China.
Yunyun FuCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Haibo ZhangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Haitao XiangBGI Research, Hangzhou 310030, China.
Xinle ChenBGI Research, Hangzhou 310030, China.
Tai ChenBGI Research, Changzhou 213299, China.
Xiaojian WuThe Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Kui WuBGI Research, Hangzhou 310030, China.
Longqi LiuBGI Research, Hangzhou 310030, China.
Xuan DongBGI Research, Hangzhou 310030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence has confirmed the presence of intratumor microbes, yet their impact on the immunopeptidome remains largely unexplored. Here we introduced an integrated strategy to identify the immunopeptidome originated from intratumor microbes. Analyzing 10 colorectal cancer (CRC) patients, we identified 154 putative microbe-derived human leukocyte antigen (HLA)-I ligands. Predominantly bacterial in origin, these peptides were notably abundant in

Indexed as

CancerImmune responseMicrobiome

Identifiers

PMID39640572
PMCPMC11617993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.