Evidence map›Paper›PMID 39640520›Full record

ArticleRSC advances2024

Formulating abiraterone acetate-HPMCAS-based amorphous solid dispersions: insights into

Manisha Choudhari, Shantanu Damle, Ranendra Narayan Saha, Sunil Kumar Dubey, Gautam Singhvi

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manisha ChoudhariDepartment of Pharmacy, Birla Institute of Technology and Science, Pilani Vidya Vihar Pilani Campus Rajasthan 333031 India gautam.singhvi@pilani.bits-pilani.ac.in.
Shantanu DamleColorcon Asia Pvt. Ltd, Verna Industrial Estate Verna Goa 403722 India.
Ranendra Narayan SahaBiophore Group of Companies Hyderabad Telangana India.
Sunil Kumar DubeyR&D Healthcare Division Emami Ltd 13, BT Road, Belgharia Kolkata 700056 India.
Gautam SinghviDepartment of Pharmacy, Birla Institute of Technology and Science, Pilani Vidya Vihar Pilani Campus Rajasthan 333031 India gautam.singhvi@pilani.bits-pilani.ac.in.ORCID https://orcid.org/0000-0002-9706-9244

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abiraterone acetate (ABTA) is used as a primary treatment for metastatic castration-resistant prostate cancer. Its low aqueous solubility results in inadequate dissolution and poor oral bioavailability (<10%), necessitating the consumption of large doses of ABTA (1000 mg per day) for desired efficacy. The aim of this study is to enhance the solubility, dissolution, and bioavailability of ABTA through amorphous solid dispersions (SDs). ABTA-SD was prepared

Identifiers

PMID39640520
PMCPMC11618532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.