Evidence map›Paper›PMID 39640373›Full record

SynthesisFrontiers in psychiatry2024

Prevalence of homosexual and bisexual orientation in patients with borderline personality disorder and associated factors - a systematic review and meta-analysis.

Ying Chi Camille Shu, Ka To Lau, Cyrus Su Hui Ho

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07639957 (What Role Does Gender Play in Relationship and Self Experiences of Individuals With Borderline Personality Disorder?), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07639957 recruitingnot on this mapstarted 2026, after this paper: background citation

What Role Does Gender Play in Relationship and Self Experiences of Individuals With Borderline Personality Disorder?

TypeobservationalSponsorUniversity Hospital HeidelbergRan2026 to 2027Enrolled15ConditionsBorderline Personality Disorder (BPD)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Psychiatric Emergency Visits of Autistic Adults With or Without Documented Borderline Personality Disorder.Autism research : official journal of the International Society for Autism Research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ying Chi Camille ShuFaculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Ka To LauFaculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Cyrus Su Hui HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This meta-analysis aimed to quantitatively evaluate the association between homosexual and bisexual orientation and borderline personality disorder (BPD), including factors contributing to the association and clinical outcomes of homosexual and bisexual patients with BPD. Methods: We systematically searched PUBMED, PsycINFO, Cochrane Library, MEDLINE, EMBASE and Web of Science for cross-sectional or cohort studies comparing the prevalence of homosexual and bisexual orientation amongst patients with BPD and controls. Results: Our search identified 7 eligible studies, with a total sample case of 636 subjects with BPD and 535 subjects without BPD. Patients with BPD had a significantly higher likelihood of homosexual and bisexual orientation (Risk ratio [RR] 3.39, 95%CI 1.88-6.12) with a pooled prevalence of 28% (95% CI 0.24-0.31; I2 73%; 7 studies, 1171 participants). Subgroup analyses validated that BPD was independently associated with higher prevalence of both homosexual (RR 8.51, 95% CI 3.36-21.54) and bisexual orientation (RR 3.82, 95% CI 1.81-8.04), but no gender difference was yielded. Childhood sexual abuse (CSA) was associated with the development of homosexual and bisexual orientation in patients with BPD. Discussion: Poorer clinical outcomes, including physical and mental health, were associated with BPD status. Further studies are necessary to evaluate the feasibility and efficacy of sexual minority-specific treatment for these patients. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=538356, identifier CRD42024538356.

Indexed as

bisexualityborderline personality disorderhomosexualitymeta-analysissexual orientation

Identifiers

PMID39640373
PMCPMC11617515

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.