Evidence map›Paper›PMID 39640336›Full record

ArticleSurgical neurology international2024

Midbrain volume in brain herniation: A volumetric analysis in operative traumatic brain injury.

Jacques Lara-Reyna, Mert Karabacak, Raymond Wedderburn, Eric Legome, Konstantinos Margetis

Abstract read
In one paragraph

Article in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacques Lara-ReynaDepartment of Neurosurgery, University of Illinois College of Medicine, Peoria, United States.
Mert KarabacakDepartment of Neurosurgery, Mount Sinai Health System, New York, United States.
Raymond WedderburnDepartment of Surgery, Division of Trauma and Acute Care, New York, United States.
Eric LegomeDepartments of Emergency Medicine, Mount Sinai Health System, New York, United States.
Konstantinos MargetisDepartment of Neurosurgery, Mount Sinai Health System, New York, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study primarily aimed to assess the volumetric attributes of the midbrain and perimesencephalic structures preoperatively and following surgical interventions in patients diagnosed with brain herniation secondary to traumatic brain injury (TBI). Methods: We evaluated patients based on radiological findings and clinical symptoms indicative of brain herniation. We performed semi-automated segmentation of the intracranial structures most relevant to trauma and of interest for the current study, such as hematoma, ventricles, midbrain, and perimesencephalic cisterns. Using preoperative and postoperative computed tomography scans, we measured and analyzed the volume of these structures. Patients were grouped based on their discharge Glasgow Coma Scale (GCS) scores: GCS 15 and non-GCS 15. Results: From May 2018 to February 2020, we included 20 patients in the study. Our volumetric analysis revealed that preoperative midbrain volume (5.84 cc vs. 4.37 cc, Conclusion: Our findings suggest that patients presenting with lesser midbrain compression preoperatively tended to have improved clinical outcomes postsurgery. Thus, we propose that this preoperative midbrain volume cut-off point holds predictive value for clinical outcomes within our cohort.

Indexed as

Brain herniationHematomaMidbrainTraumatic brain injuryVolumetric analysis

Identifiers

PMID39640336
PMCPMC11618762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.