Evidence map›Paper›PMID 39640091›Full record

ArticleCureus2024

Minoxidil Intoxication: A Case of Refractory Shock With Prolonged Supportive Care.

Simon Maigre, Virginie Meurant

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Simon MaigreEmergency Department, Centre Hospitalier Universitaire Tivoli, La Louvière, BEL.
Virginie MeurantEmergency Department, Centre Hospitalier Universitaire Tivoli, La Louvière, BEL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minoxidil, commonly used as a topical agent for alopecia, is occasionally used for refractory hypertension due to its antihypertensive properties. We report a rare case of massive minoxidil intoxication leading to refractory vasoplegic shock in a 24-year-old male. The patient ingested 120 mL of 5% minoxidil solution, resulting in vasoplegic shock. Management included fluid resuscitation and norepinephrine support. The patient required norepinephrine for 180 hours to maintain mean arterial pressure, a duration unprecedented in the literature. This case underscores the potential for prolonged vasopressor dependency following massive minoxidil ingestion and highlights the necessity for intensive symptomatic management. This report adds to the limited literature on minoxidil intoxication and suggests that extensive supportive care can be prolonged.

Indexed as

5% topical minoxidilacute toxicologymedical intensive care unit (micu)minoxidil intoxicationrefractory shock

Identifiers

PMID39640091
PMCPMC11617788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.