Evidence map›Paper›PMID 39639920›Full record

ArticleeNeurologicalSci2024

Neurobehavioral features in medication-overuse headache.

Franz Riederer, Roberto Pirrotta, Chantal Martin Soelch, Andreas R Gantenbein, Adrian Scutelnic, Antonia Klein, Christoph J Schankin, Peter S Sándor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeurologicalSci, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Franz RiedererDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Roberto PirrottaPraxis Chreis4, Zurich, Switzerland.
Chantal Martin SoelchDepartment of Psychology, University of Fribourg, Fribourg, Switzerland.
Andreas R GantenbeinDepartment of Neurology, University Hospital Zurich, University of Zurich, Switzerland.
Adrian ScutelnicDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Antonia KleinDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Christoph J SchankinDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Peter S SándorDepartment of Neurology, University Hospital Zurich, University of Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medication-overuse headache (MOH) has been related to the spectrum of dependence behavior and impaired orbitofrontal cortex function. Alexithymia is a trait comprising deficits in identifying self-emotions and perception. It was the aim of the study to investigate impulsivity and alexithymia, in patients with MOH and perform correlations with cerebral grey matter. Material and methods: Patients with chronic migraine and MOH according to ICHD criteria from a tertiary headache clinic and healthy controls were investigated by a single psychiatrist, using clinical scales for self-control (BIS-11) and alexithymia (TAS-20) and screened for dependence based on DSM-IV criteria. Correlations of BIS-11 and TAS-20 with cerebral grey matter were analysed with the SPM based toolbox CAT12, using high resolution T1weighted MRI-Sequences acquired on a 3 T scanner. Results: MRI data were available from 30 MOH patients (24 women) and 47 healthy controls (26 women). MOH patients had increased impulsivity (62.2 ± 11.1 vs. 55.7 ± 7.2; Conclusions: The present study suggests a neurobehavioral basis for MOH, consisting of impaired impulse control, and self-perception along with features of substance dependence. Although decreased orbitofrontal cortex volume was confirmed in this MOH cohort, impulsivity and alexithymia were not correlated with this structural abnormality.

Indexed as

AlexithymiaImpulsivityMedication-overuse headacheOrbitofrontal cortexSubstance dependence

Identifiers

PMID39639920
PMCPMC11617310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.