Evidence map›Paper›PMID 39639720›Full record

ArticleAIDS (London, England)2025

The relationship between HIV and reading performance for children in Tanzania.

Silvia Bonacina, Jonathan D Lichtenstein, Christopher Niemczak, Albert Magohe, Abigail Fellows, Trent Nicol, Enica Massawe, Nina Kraus, Jay C Buckey

Abstract read
In one paragraph

Article in AIDS (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silvia BonacinaDepartment of Communication Sciences and Disorders, Northwestern University, Chicago, IL, United States.
Jonathan D LichtensteinGeisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH, United States.
Christopher NiemczakGeisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH, United States.
Albert MagoheDar Dar Programs, Dar es Salaam, United Republic of Tanzania.
Abigail FellowsGeisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH, United States.
Trent NicolDepartment of Communication Sciences and Disorders, Northwestern University, Chicago, IL, United States.
Enica MassaweMuhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania.
Nina KrausDepartment of Communication Sciences and Disorders, Northwestern University, Chicago, IL, United States.
Jay C BuckeyGeisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH, United States.

Funding

Novel pediatric neurocognitive screening using central auditory testsR01HD095277 · NICHD · DARTMOUTH COLLEGE · PI JAY C BUCKEY · 2018 to 2026
$5.9M
NICHD NIH HHS R01 HD095277
6 · The paper itself

Abstract

objectiveChildren with HIV (CWH) are at increased risk for cognitive and developmental delays, although HIV's influence on reading development remains unclear. Research using internationally validated reading measures with control for factors known to influence literacy outcomes is needed. The Early Grade Reading Assessment (EGRA) is a tool for assessing students' progress toward reading that has been validated across countries. It was administered to a cohort of children living with and without HIV (CWH/CWOH) and data on other factors that might affect literacy were also measured. DESIGN AND

methods388 children [217 children without HIV (CWOH) and 171 CWH; ages 3-8] drawn from a longitudinal study in Dar es Salaam, Tanzania completed the EGRA. EGRA performance between CWH and CWOH was compared adjusting for age, socioeconomic status, years of education, English learning, and type of school (public or private).

resultsDespite the biological and environmental confounders, CWH performed significantly worse than CWOH on the Letter Name Knowledge subtest, the Syllable subtest, the Non-Word subtest, and the Reading Comprehension subtest. The difference approached significance for the Oral Reading Fluency subtest.

conclusionsCWH performed worse than CWOH on the EGRA, indicating literacy skill development in CWH needs early intervention. Longitudinal analyses, including electrophysiological and behavioral data, are needed to find the factors associated with poor reading and literacy performance in CWH.

Indexed as

HIV InfectionsReadingChildChild, PreschoolHumansLiteracyLongitudinal StudiesMaleTanzania

Identifiers

PMID39639720
PMCPMC11631034

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.