Trial reportBMC oral health2024
Low-level laser therapy on soft tissue healing after implantation: a randomized controlled trial.
Trial report in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Near Infrared Light on Surgical Wound Healing: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Laser-assisted pontic site soft tissue healing prior to fixed partial dentures: a randomized placebo-controlled clinical trial.BMC oral health · 2026Trial
- Photobiomodulation in Dental Implant Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Dentistry journal · 2026Review
- Review
- Effect of simultaneous application of low-level diode laser and leukocyte platelet-rich fibrin on gingival tissue healing: an in vitro investigation.Scientific reports · 2026Article
- Recent Advances in Regenerative Therapies in Periodontology.Dentistry journal · 2025Review
- Effects of platelet-rich fibrin combined with low-level erbium laser on soft and hard tissues and bone regeneration around implants.American journal of translational research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundTo explore the effect of low-level laser therapy (LLLT) on the healing of soft tissue around the implant after flap implantation and explore the possible mechanism.
methodsA total of 58 patients who underwent implant surgery were enrolled, with a total of 70 implants. They were randomly divided into the LLLT group and the control group. The LLLT group underwent LLLT with Nd:YAG (Fotona, 1064 nm) immediately after surgery and on the 2nd and 3rd day in the surgical area, while the control group did not receive any intervention. Pain assessment was performed in the first 3 days after surgery. The weight of peri-implant crevicular fluid (PICF), modified sulcus bleeding index (mSBI), gingival index (GI), and the expression levels of tumor necrosis factor-α (TNF-α), and vascular endothelial growth factor (VEGF) on the 7th and 14th days after surgery were evaluated.
resultsOn the first 3 days after surgery, the pain score of the LLLT group was significantly lower than that of the control group. On the 7th and 14th day after surgery, the PICF volume, mSBI, GI, and TNF-α levels of the LLLT group were lower than those of the control group. The VEGF levels in the LLLT group were significantly higher than that in the control group.
conclusionsLLLT can promote the healing of the soft tissue after implantation, effectively relieve postoperative pain, improve clinical indicators, reduce TNF-α, and increase the expression level of VEGF, which is worthy of clinical application.
trial registrationRetrospectively Registered Trials ChiCTR2400087562 (07/30/2024).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.